Animal Cloning Drawbacks An-Overview

Ibtisham, Fahar; Niu, Yanfeng; Wang, Zhi; Wu, Jiang; Xiao, Mingzhao; An, Lilong

doi:10.15406/jdvar.2016.03.00087

Cited by 3 publications

(1 citation statement)

References 45 publications

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“…For a variety of reasons, many scientists and regular people are against cloning. Due to the high failure rate of cloned animal growth from fetus to adulthood, it has been deemed an ineffective Technology for Carbon Neutral Animal Breeding DOI: http://dx.doi.org/10.5772/intechopen.110383 technique up until this point [43]. In this instance, selective breeding was successful in reducing methane production by 20% over the course of ten years, but at the cost of increasing the ad hoc weight of methane in the selection index to 33% and slowing the genetic gain for production traits from 6 to 18%.…”

Section: Selecting For Low-methane Producing Ruminantsmentioning

confidence: 99%

Technology for Carbon Neutral Animal Breeding

Mekonnen¹

2024

Veterinary Medicine and Science

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Animal breeding techniques are to genetically select highly productive animals with less GHG emission intensity, thereby reducing the number of animals required to produce the same amount of food. Shotgun metagenomics provides a platform to identify rumen microbial communities and genetic markers associated with CH4 emissions, allowing the selection of cattle with less CH4 emissions. Moreover, breeding is a viable option to make real progress towards carbon neutrality with a very high rate of return on investment and a very modest cost per tonne of CO2 equivalents saved regardless of the accounting method. Other high technologies include the use of cloned livestock animals and the manipulation of traits by controlling target genes with improved productivity.

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Section: Selecting For Low-methane Producing Ruminantsmentioning

confidence: 99%

Technology for Carbon Neutral Animal Breeding

Mekonnen¹

2024

Veterinary Medicine and Science

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Scientific and Ethical Implications of Human and Animal Cloning

Shafique¹

2020

IJSTS

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Approbating progressive technology of cattle cloning

Кириенко,

Миронова,

Икономов

et al. 2024

Проблемы Биологии Продуктивных Животных

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Перенос ядер соматических клеток (SomaticCellNuclearTransfer, SCNT) до настоящего времени был наиболее эффективным и жизнеспособным методом размножения ценных или находящихся под угрозой исчезновения животных. Более 99% эмбрионов или живого потомства, о которых ранее сообщалось, были получены с помощью подхода, основанного на микроманипуляциях, т.е. с использованием традиционного SCNT. При «ручном» клонировании (Hand-madeCloning, HMC) процедуры энуклеации ооцитов и реконструирования эмбрионов осуществляются в отсутствии zonapellucida, и все манипуляции проводятся без использования микроманипуляторов. К настоящему времени, в мире были получены положительные результаты по получению клонированного потомства от крупного рогатого скота, буйволов, овец, свиней и лошадей с использованием HMC. Цель исследования – апробация технологии клонирования крупного рогатого скота по методу HMC.Яичники коров голштинской породы были получены с местной бойни в течение 20–30 мин после убоя и доставляныв лабораторию в течение 3 ч. Изучена эффективность основных этапов технологии клонирования методом HMC: дозревание ооцитов крупного рогатого скота invitro, с последующим их использованием в качестве доноров цитопластов; получение культуры соматических клеток от высокопродуктивной коровы голштинской породы, использование её в качестве клеток доноров кариопластов; активация, культивирование и трансплантация реконструированных эмбрионов корове-реципиенту, генетическое тестирование полученного потомства. В результате исследования впервые в Российской Федерации получена клонированная тёлочка голштинской породы с использованием метода HMC. Полученные результаты свидетельствуют о возможности практического использования технологии HMC для получения потомства высокопродуктивных коров. Somatic cell nuclear transfer (SCNT) was up to date the most effective and viable method for propagating valuable or endangered animals. More than 99% of embryos or living offspring previously reported were obtained using a micromanipulation approach, i.e. using traditional SCNT. With hand-made cloning (HMC), the procedures of oocyte enucleation and embryo reconstruction are carried out in the absence of the zona pellucida, and all manipulations are carried out without the use of micromanipulators. To date, using HMC, positive results have been obtained in the world in obtaining cloned offspring from cattle, buffaloes, sheep, pigs and horses. The aim of this work is to test the technology of cloning cattle using the HMC method. The selection of materials for the study and the organization of calving were carried out on the basis of the dairy farm using Holstein cows. Cow ovaries were obtained from a local slaughterhouse within 20–30 minutes after slaughter and delivered to the laboratory within 3 hours. The effectiveness of the main stages of cloning technology using the HMC method was studied: maturation of cattle oocytes in vitro, followed by their use as cytoplast donors; obtaining a culture of somatic cells from a highly productive Holstein cow and using it as karyoplast donor cells; activation, cultivation and transplantation of reconstructed embryos into a recipient cow, genetic testing of the resulting offspring and cow recipient.As a result of the study, for the first time in the Russian Federation, a cloned Holstein heifer was obtained using the HMC method. The results obtained indicate the possibility of practical use of HMC technology to produce offspring of highly productive cows.

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Animal Cloning Drawbacks An-Overview

Cited by 3 publications

References 45 publications

Technology for Carbon Neutral Animal Breeding

Technology for Carbon Neutral Animal Breeding

Scientific and Ethical Implications of Human and Animal Cloning

Approbating progressive technology of cattle cloning

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