Animal Experimental Study to Test Application of Intelligent Pressure Control Device in Monitoring and Control of Renal Pelvic Pressure During Flexible Ureteroscopy

Zhu, Xianxin; Song, Leming; Xie, Donghua; Peng, Zhe; Guo, Shu-Lin; Deng, Xiaolin; Liu, Shengfeng; Fan, Daiming; Huang, Jianrong; Liu, Tairong; Du, Chengchao; Zhu, Ling; Yang, Zhongsheng; Peng, Guang-Hua; Hu, Min; Yao, Lei; Zeng, Min; Zhong, Jiuqing; Qing, Wen; Ye, Zhangqun

doi:10.1016/j.urology.2016.02.022

Cited by 29 publications

(14 citation statements)

References 16 publications

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“…Flexible ureteroscopy (FURS) has been applied in recent years to the treatment of urinary stones, which presents overt advantages over other techniques, including improved resolution and increased optical field, high stone-free rate, reduced risk of bleeding, limited surgical injury, good repeatability, and speedy recovery; in addition, further miniaturization is possible. [10][11][12] In children and infants, who have a relatively high stone recurrence rate, 13 flexible ureteroscopy could be performed repeatedly. FURS and holmium laser lithotripsy in treating infants and children has been previously assessed.…”

Section: Introductionmentioning

confidence: 99%

Treatment of upper urinary tract stones with flexible ureteroscopy in children

Xiao

Wang

et al. 2018

CUAJ

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Section: Introductionmentioning

confidence: 99%

Treatment of upper urinary tract stones with flexible ureteroscopy in children

Xiao

Wang

et al. 2018

CUAJ

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“…The perfusion pressure chosen to keep constant in this study was 1.96Kpa (20cmH2O), which was slightly higher than that of human renal pelvis pressure 0.98kpa (10cmH2O). However, under this perfusion pressure, the urodynamic parameters of the upper urinary tract did not change abnormally, indicating that this pressure was within the safe pressure range of renal pelvic perfusion and was significantly lower than the clinically accepted safety pressure of renal pelvis perfusion during percutaneous nephroscopic surgery (30mmHg) [11]. Second, because the experimental site is located in Kunming (latitude 25 °02: 11\ "north, longitude 102 °42: 31\" east, the average altitude is about 1891 m), the background altitude is high and the atmospheric pressure is low, so the standard pressure reference value of 1.96Kpa is adopted.…”

Section: Analysis Of Urodynamic Parameters Of Upper Urinary Tract In mentioning

confidence: 74%

Quantitative Evaluation of Upper Urinary Tract Pump Function in Pigs With Acute Unilateral Lower Ureteral Obstruction by 640-slice Dynamic Volume CT

Mao

Peng

et al. 2021

Preprint

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Background: It is a challenging problem to differentiate obstructive hydronephrosis from non-invasive evaluation of renal pelvis and ureteral motility in patients. The purpose of this study was to explore the value of 640-slice dynamic volume CT (DVCT) in quantitative measurement of upper urinary tract (UUT) pump function after acute unilateral lower ureteral obstruction in pigs. Methods: In this study, perfusion pig model was made by constant pressure perfusion test of renal pelvis and left nephrostomy. The perfusion and pressure measuring devices were connected to create the state of no obstruction, acute obstruction of the lower part of the left ureter. After successful modeling, continuous dynamic volume scanning of bilateral renal excretion phase was performed with 640-slice DVCT, and pump functions of the renal pelvis and part of the upper ureter were calculated and analyzed. No obstruction, acute obstruction of the lower part of the left ureter. Pump functions of the renal pelvis and part of the upper ureter. Results: Results showed after LUUT fistulostomy, the time difference between the average UUTs volume and positive volume value increased gradually, and the calculated flow velocity decreased, which was significantly different from that of the RUUT. The volume difference of the LUUT increased significantly in mild obstruction. In the bilateral control, the volume change rate of the LUUT increased in mild obstruction and decreased in severe obstruction, and there was significant difference between the left and the right side. Conclusion: The continuous dynamic volume scan and measurement of 640-slice DVCT can obtain five pump function data of UUT in pigs with acute lower ureteral obstruction.

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“…The perfusion pressure chosen to remain constant in this study was 1.96 kPa (20 cmH 2 O), which was slightly higher than the human renal pelvis pressure of 0.98 kPa (10 cmH 2 O). However, under this perfusion pressure, the urodynamic parameters of the upper urinary tract did not change abnormally, indicating that this pressure was within the safe pressure range of renal pelvic perfusion and was significantly lower than the clinically accepted safe pressure of renal pelvis perfusion during percutaneous nephroscopic surgery (30 mmHg) [ 11 ]. Second, because the experimental site is located in Kunming (latitude 25°02: 11\"north, longitude 102°42: 31\"east, average altitude of approximately 1891 m), the background altitude is high and the atmospheric pressure is low, so the standard pressure reference value of 1.96 kPa was adopted.…”

Section: Discussionmentioning

confidence: 99%

Quantitative evaluation of upper urinary tract pump function in pigs with acute unilateral lower ureteral obstruction by 640-slice dynamic volume CT

Mao

Peng

et al. 2021

BMC Urol

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Background It is a challenging problem to differentiate obstructive hydronephrosis from noninvasive evaluation of renal pelvis and ureteral motility in patients. The purpose of this study was to explore the value of 640-slice dynamic volume CT (DVCT) in the quantitative measurement of upper urinary tract (UUT) pump function after acute unilateral lower ureteral obstruction in pigs. Methods In this study, a perfusion pig model was constructed by constant pressure perfusion testing of the renal pelvis and left nephrostomy. The perfusion and pressure measuring devices were connected to create a state of no obstruction and acute obstruction of the lower part of the left ureter. After successful modelling, continuous dynamic volume scanning of the bilateral renal excretion phase was performed with 640-slice DVCT, and pump functions of the renal pelvis and part of the upper ureter were calculated and analysed. No obstruction or acute obstruction of the lower part of the left ureter was observed. Pump functions of the renal pelvis and part of the upper ureter were determined. Results The results showed that after LUUT fistulostomy, the time difference between the average UUT volume and positive volume value increased gradually, and the calculated flow velocity decreased, which was significantly different from that of the RUUT. The volume difference of the LUUT increased significantly in mild obstruction. In the bilateral control, the volume change rate of the LUUT increased with mild obstruction and decreased with severe obstruction, and there was a significant difference between the left and right sides. Conclusion The continuous dynamic volume scan and measurement of 640-slice DVCT can obtain five pump function datasets of UUT in pigs with acute lower ureteral obstruction.

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Animal Experimental Study to Test Application of Intelligent Pressure Control Device in Monitoring and Control of Renal Pelvic Pressure During Flexible Ureteroscopy

Cited by 29 publications

References 16 publications

Treatment of upper urinary tract stones with flexible ureteroscopy in children

Treatment of upper urinary tract stones with flexible ureteroscopy in children

Quantitative Evaluation of Upper Urinary Tract Pump Function in Pigs With Acute Unilateral Lower Ureteral Obstruction by 640-slice Dynamic Volume CT

Quantitative evaluation of upper urinary tract pump function in pigs with acute unilateral lower ureteral obstruction by 640-slice dynamic volume CT

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