Anion Sensors

Terpyridine-Functionalized Calixarenes: Synthesis, Characterization and Anion Sensing Applications

“…Anion receptors that were constructed using the calix [4]arene scaffold, containing linkers with amide functionalities and pyridine moieties, were previously reported by our group [31]. We showed by 1 H NMR studies that these receptors were responsive to carboxylates and H 2 PO 4…”

“…The calixarene scaffold has been frequently used in the construction of anion (and other) sensors as it imparts a high degree of pre-organization of the recognition groups leading to enhanced binding affinities of target molecules or ions [24,25]. The current work details the development of calixarene-based sensors for anions that have been synthesized in two steps from a [4]arene scaffold with carboxylic acid functionalities at the lower rim was coupled to an amine derivative bearing a terpyridine moiety. The resulting compound was metallated by stirring it overnight with the appropriate lanthanide(III) triflate salt to form either the Eu(III) or Tb(III) complex.…”

“…The current work details the development of calixarene-based sensors for anions that have been synthesized in two steps from a calixarene derivative. A calix [4] arene scaffold with carboxylic acid functionalities at the lower rim was coupled to an amine derivative bearing a terpyridine moiety. The resulting compound was metallated by stirring it overnight with the appropriate lanthanide(III) triflate salt to form either the Eu(III) or Tb(III) complex.…”

Fluorescent benzimidazo[1,2-a]quinolines: synthesis, spectroscopic and computational studies of protonation equilibria and metal ion sensitivity

“…Novel optical pH sensors and probes are usually characterized by their aqueous solution pK a values determined by spectrophotometry or spectrofluorometry. [1][2][3][4] Optical evaluation of the concentrations of the acidic (HA) and basic forms (A À ) is based on the Henderson-Hasselbach eqn (1): 31 pH ¼ pK a þ log A À ½ HA ½…”

“…Fluorescence spectroscopy in particular has long been viewed as a powerful tool for basic research in the biological sciences due to the notable progress made in instrumentation, and the synthesis and availability of novel fluorophores. [1][2][3][4] The selective recognition and detection of transition metal cations are of great interest for many scientific studies due to their importance in chemical, biological, biomedical or environmental processes. [5][6][7] Many of them are involved in the most important biological and biochemical processes, such as transmission of nerve impulses, muscle contraction and regulation of cell activity.…”