Anion transport and binding properties of N N′-(phenylmethylene)dibenzamide based receptors

Abstract

Dedicated to friend and mentor Professor Jonathan L. Sessler on the occasion of his 60th birthday.The anion transport and binding properties of a series of bis-amide based compounds have been studied in POPC lipid bilayers. The compounds display evidence of aggregation in solution with single crystal X-ray crystallographic analysis showing hydrogen bonding between the amide substituents of adjacent receptors in the solid state.

Design and synthesis of bioactive small molecule anionophores inspired on natural products

“…have shown that they exchange Cl -/NO 3 better than Cl -/HCO 3 and both are worse than the corresponding values obtained for bis(ureas). 79 Jeong et al have demonstrated that bis(ureas) based on cis-or trans-amide linkage display really different ionophoric activity as a function on the amide conformation. Trans-amide conformation is nearly no active.…”