Annular lesions in dermatology

Erythema papulatum centrifugum developing around melanoma

“…Other differential diagnoses for EPC include erythema annulare centrifugum (EAC), erythema gyratum repens (EGR), necrolytic migratory erythema and Meyerson phenomenon. 3 In our patient, neither the trailing scales behind an advancing border like superficial EAC, nor the concentric wood grain pattern of EGR, were observed. There was no localized halo of eczema within the pigmented lesion as in Meyerson phenomenon.…”

“…2 It is theorized that SLNS may be a paradominant trait and is due to a localized defect in neural crest melanoblasts at an early developmental age. 3 Speckled lentiginous nevus syndrome may be part of several complex syndromes, and each of them is associated with different cutaneous syndromes. Macular SLN is considered to be the hallmark of phacomatosis spilorosea (phacomatosis pigmentovascularis type IIIa/b), whereas papular SLN is typically present in phacomatosis pigmentokeratotica and SLNS.…”

Recurrent Finkelstein-Seidlmayer Disease in Four First-degree Relatives

“…Furthermore, recurrent FSD has been observed in an infant with Wiskott-Aldrich syndrome, an X-linked immunodeficiency characterized by thrombocytopenia, eczema, recurrent infections and increased risk of autoimmune disorders and malignancies (3). Drug-induced cutaneous vasculitides presenting with annular lesions resembling FSD have also been observed occasionally (4).…”

Tissue-Resident Memory T Cells in Skin Diseases: A Systematic Review

“…The long-lived, non-recirculating characteristic of autoreactive dysregulated TRMs can also cause skin diseases [23]. Diseases such as psoriasis, vitiligo and cutaneous Tcell lymphoma (CTCL) are characterized by well-demarcated plaques [24], and lesions often recur in the same location once therapy is discontinued, indicating a type of disease memory [25]. These lesions are often highly enriched with pathogenic TRMs [26,27], and it has been suggested that TRMs harbor a disease memory [27].…”