Annular lichenoid dermatitis of youth – a further case in a 12-year-old girl

Kleikamp, Stefanie; Kutzner, Heinz; Frosch, Peter J.

doi:10.1111/j.1610-0387.2007.06575.x

Cited by 4 publications

(13 citation statements)

References 12 publications

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“…who reported 23 patients suffering from this condition. Since then, three additional cases were reported 2–4 . We present here a new case of ALDY and briefly review the main features of this condition.…”

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confidence: 91%

“…The lesions have often a raised erythematous border and a hypopigmented centre. They are as a rule asymptomatic, although mild intermittent pruritus was noted in one case 4 . The main clinical differential diagnoses include morphea, mycosis fungoides, annular erythemas and inflammatory vitiligo.…”

mentioning

confidence: 98%

“…The main clinical differential diagnoses include morphea, mycosis fungoides, annular erythemas and inflammatory vitiligo. Histologically, ALDY manifests as a lichenoid interface dermatitis with massive necrosis/apoptosis of keratinocytes (colloid bodies) into the tips of rete ridges, basal cell vacuolization and a band‐like lymphocytic infiltrate in the papillary dermis, made predominantly of CD4+/CD45R0 + T cells, 1 whereas intraepidermal lymphocytes may express the CD8/TIA1 cytotoxic phenotyoe 4 . The infiltrate is polyclonal, 1 allowing separation of ALDY from (hypopigmented) mycosis fungoides, the most important differential diagnosis.…”

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confidence: 99%

“…Transient remissions can be achieved with topical or systemic corticosteroids or PUVA treatment, but the lesions recur after treatment discontinuation 1,2 . One case reportedly responded to topical tacrolimus 4 …”

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confidence: 99%

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Annular lichenoid dermatosis of youth

Tsoïtis¹,

Kanitakis

Kyamidis³

et al. 2009

Acad Dermatol Venereol

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Treatment with itraconazol (400 mg once a week) was added for onycomicosis. Two weeks later, the patient was discharged from the hospital with substantial improvement of oedema and erythema, healing of the ulcers and pain relief.This patient represents a typical case of primary erytromelalgia. Diagnosis of this condition is important because proper counselling can enable the patient to minimize the severity and frequency of the painful episodes. Davis et al. in a retrospective review of 168 patients with erythromelalgia showed increased mortality in patients with erythromelalgia compared with matched control subject. 5 Erythromelalgia decreases quality of life and makes normal social function, work and family life impossible. There is no effective therapy for erythromelalgia. Most available clinical evidence regarding treatment of erythromelalgia comes from anecdotal studies. Treatment options include sodium channel blockers, intravenous lidocaine, prostaglandin analogs, serotonin reuptake inhibitors, venlafaxin, 6 opiods, mexiletine, gabapentin and betaadrenergic drugs; however, further research is needed to develop more effective treatments. 7

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confidence: 91%

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confidence: 98%

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confidence: 99%

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confidence: 99%

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Annular lichenoid dermatosis of youth

Tsoïtis¹,

Kanitakis

Kyamidis³

et al. 2009

Acad Dermatol Venereol

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“…Annular lichenoid dermatitis of youth (ALDY) is a recently described dermatosis of unknown origin, first described in 2003 1 . Since the original description of 23 patients with this condition, 12 additional cases have been reported, most of them in white patients 2–8 and one in a Korean one 9 . We present here the first case of ALDY in a Japanese patient, who also happens to be the youngest one diagnosed with ALDY so far.…”

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Annular lichenoid dermatosis of youth: Report of the first Japanese case and published work review

Huh

Kanitakis

2010

The Journal of Dermatology

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Annular lichenoid dermatosis of youth is a recently described skin disease with particular clinicopathological features. It has been so far described in 35 patients, all of whom (but one) were white. We report here the first case of annular lichenoid dermatosis of youth in a Japanese patient, who is the youngest reported with this diagnosis, and briefly review the salient clinicopathological features of this condition. Our observation shows that annular lichenoid dermatosis of youth can also affect Japanese patients; therefore, Japanese dermatologists should be aware of this particular dermatosis.

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