“…In the present study, the MCA RI did not change significantly over the assessment period and betamethasone treatment had no effect on the Doppler flow velocity of the MCA. In agreement with these results, Nozaki et al [10] and Urban et al [14] found no significant changes in MCA indices.…”
Section: Discussionsupporting
confidence: 67%
“…According to Nozaki et al [10], betamethasone therapy led to a reduction in the UmA and ductus venosus PI after 24 hours; this reduction continued until 48 hours after treatment. By contrast, Urban et al [14] found no significant changes in the UmA PI. In a study in Australia, Robertson et al [11] observed that betamethasone therapy was associated with a transient reduction in the end-diastolic flow of the UmA for two-thirds of fetuses with FGR.…”
“…In the present study, the MCA RI did not change significantly over the assessment period and betamethasone treatment had no effect on the Doppler flow velocity of the MCA. In agreement with these results, Nozaki et al [10] and Urban et al [14] found no significant changes in MCA indices.…”
Section: Discussionsupporting
confidence: 67%
“…According to Nozaki et al [10], betamethasone therapy led to a reduction in the UmA and ductus venosus PI after 24 hours; this reduction continued until 48 hours after treatment. By contrast, Urban et al [14] found no significant changes in the UmA PI. In a study in Australia, Robertson et al [11] observed that betamethasone therapy was associated with a transient reduction in the end-diastolic flow of the UmA for two-thirds of fetuses with FGR.…”
“…The possible negative effects seem associated more with dexamethasone than betamethasone (134). Although a controlled clinical trial showed no increased incidence of birth defects among children born to asthmatic mothers receiving steroids compared to the general population (135), a systematic review of studies of pregnant women taking glucocorticoids during pregnancy demonstrated an increased risk of cleft palate (odds ratio of 3.4 [95% confidence interval 1.97-5.69]) (136).…”
Section: Immunosuppression and Reproductionmentioning
“…Возможные негативные эффекты оказались более свойственны дексаметазону, чем бетаметазону [66]. К тому же метаанализ показал, что только бетаметазон, а не декса-метазон, значительно уменьшает неонатальную смерт-ность [67].…”
Section: п р и м е н е н и е л е к а р с т в е н н ы х п р е п а р а unclassified
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