The chapter presents different types of metamaterials, their historical evolution, physical properties, and applications in antennas design. Metamaterials are artificial structures that offer electric and magnetic properties that are not found in nature, such are negative permittivity and negative permeability. These properties are used in antennas design in order to obtain ultrawide bandwidth, high gain, and electrically small structures. Modern wireless mobile communication uses 5G technology and multi-input multi-output (MIMO) antennas, which are based on high-frequency transmission and ultrawide band. Metamaterials are very good candidate for this technology, where miniaturized antennas loaded with metamaterials structures are used. Recently, electromagnetic sensors were used for liquid identification in biological and medical substances based on metamaterials for the sake of high sensitivity and better classification. Different metamaterial types are used in these sensors, depending on the nature of liquid and the associated application.