Anteromedial GPi deep brain stimulation in Tourette syndrome: The first case series from Iran

Therapeutic Neurostimulation in Obsessive-Compulsive and Related Disorders: A Systematic Review

“…Investigation of motor and phonic tic subdomains did not demonstrate a clear pattern across thalamic and GPi targets. Thus, there was comparable change for motor and phonic tics (within 5-15%) [182,183,[185][186][187]189,[192][193][194]196,197].…”

“…Closed-label investigations led to 10% and 22% improvement [192,195]. Open-label treatment led to 14%, and 47% improvement in the short term [186,191], while long-term therapy (1-4 years) led to 40-63% change [187,[195][196][197].…”

Bilateral Posteroventral GPi-DBS in a Patient with Tourette’s Syndrome – A Rapidly Effective But Under-utilized Therapy

“…[ 3 4 6 ] Similarly, Azimi et al . [ 13 ] showed a marked improvement in tic severity in the evaluations 1 year after the GPi-DBS therapy in six patients with TS (reduction in the TYGTSS score from 75.6 to 28.3). On the other hand, in most of these studies, the assessments regarding the outcome were performed in the chronic period of the treatment, while the data about the effects in the early period were lacking.…”

Deep Brain Stimulation In Iran: Where It Began and Where It Goes

“…By reporting approximately successful results concerning the dosage of medications and improvement of motor symptoms, they progressed to a new chapter in treating those affected by PD's refractory symptoms. During recent years, DBS has been used for other varieties of neuropsychiatric disorders in Iran, such as dystonia (4, 5), Tourette syndrome (6), and Holmes tremor (7). However, DBS is still in the embryonic stages of its life in Iran since this procedure is mostly limited to the hospitals affiliated with medical universities (e.g., Shahid Beheshti, Iran, and Shiraz Universities of Medical Sciences).…”