Anti–bacterial activity and brine shrimp lethality bioassay of methanolic extracts of fourteen different edible vegetables from Bangladesh

Ullah, Mujeeb; Haque, Md. Fazlul; Urmi, Kaniz Fatima; Zulfiker, Abu Hasanat Md.; Anita, Elichea Synthi; Begum, Momtaj; Hamid, Kaiser

doi:10.1016/s2221-1691(13)60015-5

Cited by 90 publications

(66 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The seeds are regarded as valuable in the treatment of urinary problems, digestive problems and cardiovascular diseases (11). Studies demonstrated a variety of pharmacological activities, including hypoglycemic (12, 13), hypocholesterolemic, antioxidant, analgesic, antiinflammatory, skeletal muscle relaxant, smooth muscle relaxant, neuroprotective (14), anxiolytic, sedative, anticonvulsant, antiulcerogenic, bronchodilatory, wound healing, and antifungal effects (15). It contains a variety of bioconstituents, including catecholamines, l-noradrenaline, dopamine, α-amyrin, β-amyrin and portuloside A (16,17,18).…”

Section: Introductionmentioning

confidence: 99%

Determination of Aflatoxins in Medicinal Plants by High-Performance Liquid Chromatography–Tandem Mass Spectrometry

Mujeeb

Ahmad

et al. 2013

J Pharm Pharm Sci

View full text Add to dashboard Cite

-Purpose. The intention of the proposed work is to study the presence of the aflatoxins B 1 , B 2 , G 1 and G 2 in medicinal plants, namely Mucuna pruriens, Delphinium denudatum and Portulaca oleraceae. Methodology. The aflatoxins were extracted, purified by immunoaffinity column chromatography and analysed by high-performance liquid chromatography-tandem quadrupole mass spectrometry with electrospray ionisation (HPLC-MS/MS). Fungal count was carried out in PDA media. Results. A good linear relationship was found for AFB 1 , AFB 2 , AFG 1 and AFG 2 at 1-10 ppb (r>0.9995). The analyte accuracy under three different spiking levels was 86.7-108.1 %, with low per cent relative standard deviations in each case. The aflatoxins can be separated within 5 to7 min using an Agilent XDB C18-column. We found that AFB 1 and AFB 2 were in trace amounts below the detection limit in M. pruriens whilst they were not detected in D. denudatum. P. oleraceae was found to be contaminated with AFB 1 and AFB 2 . AFG 1 and AFG 2 were not detected in M. pruriens, P. oleraceae and were below the detection limit in D. denudatum. This was consistent with very low numbers of fungal colonies observed after 6 hr of incubation. Conclusion. The analytical method developed is simple, precise, accurate, economical and can be effectively used to determine the aflatoxins in medicinal plants and therefore to control the quality of products. The aflatoxin levels in the plant extracts examined were related to the minimal fungal load in the medicinal plants examined.

show abstract

Section: Introductionmentioning

confidence: 99%

Determination of Aflatoxins in Medicinal Plants by High-Performance Liquid Chromatography–Tandem Mass Spectrometry

Mujeeb

Ahmad

et al. 2013

J Pharm Pharm Sci

View full text Add to dashboard Cite

show abstract

“…A report was demonstrated on this plant, it is used by the Lohit community of Arunachal Pradesh, India for treatment of inflammatory disorders (Namsa et al, 2009) and some recent studies evidenced that the plant possesses antinociceptive activity and hypoglycemic activity Hossan et al, 2011) and also traditionally it was used in Bangladesh to manage the blood sugar level in diabetic patients and to relieve pain . A current report has validated on anti-bacterial and cytotoxic actions in methanolic extract of this plant (Ullah et al, 2013).…”

Section: Introductionmentioning

confidence: 75%

<i>In vitro</i> thrombolytic, anthelmintic, anti-oxidant and cytotoxic activity with phytochemical screening of methanolic extract of <i>Xanthium indicum</i> leaves

Ghosh

Banik

Islam

2015

Bangladesh J Pharmacol

View full text Add to dashboard Cite

Xanthium indicum is an important medicinal plant traditionally used in Bangladesh as a folkloric treatment. The current study was undertaken to evaluate thrombolytic, anthelmintic, anti-oxidant, cytotoxic properties with phytochemical screening of methanolic extract of X. indicum leaves. The analysis of phytochemical screening confirmed the existence of phytosetrols and diterpenes. In thrombolytic assay, a significant clot lysis was observed at four concentrations of plant extract compare to the positive control streptokinase (30,000 IU, 15,000 IU) and negative control normal saline. The extract revealed potent anthelmintic activity at different concentrations. In anti-oxidant activity evaluation by two potential experiments namely total phenolic content determination and free radical scavenging assay by 2, 2-diphenylpicrylhydrazyl (DPPH), the leaves extract possess good anti-oxidant property. In the brine shrimp lethality bioassay, the crude extract showed potent (LC50 1.3 μg/mL) cytotoxic activity compare to the vincristine sulfate as a positive control (LC50 0.8 μg/mL).

show abstract

“…The use of antimicrobials is to prevent the creation of a solution of the chemical residues of antibiotics [16][17][18][19][20][21][22][23][24][25][26][27] .…”

Section: Discussionmentioning

confidence: 99%

Determination of antibiotic residues in the pasteurized milk produced in West Azerbaijan province, North West of Iran

Forouzan¹,

Rahimirad²,

Seyedkhoei³

et al. 2014

JCLM

View full text Add to dashboard Cite

Anti–bacterial activity and brine shrimp lethality bioassay of methanolic extracts of fourteen different edible vegetables from Bangladesh

Cited by 90 publications

References 53 publications

Determination of Aflatoxins in Medicinal Plants by High-Performance Liquid Chromatography–Tandem Mass Spectrometry

Determination of Aflatoxins in Medicinal Plants by High-Performance Liquid Chromatography–Tandem Mass Spectrometry

<i>In vitro</i> thrombolytic, anthelmintic, anti-oxidant and cytotoxic activity with phytochemical screening of methanolic extract of <i>Xanthium indicum</i> leaves

Determination of antibiotic residues in the pasteurized milk produced in West Azerbaijan province, North West of Iran

Contact Info

Product

Resources

About