Anti–Glycation Aging Prevention Strategies

Boiarska, Z.

doi:10.26693/jmbs04.06.309

Cited by 2 publications

(1 citation statement)

References 37 publications

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“…There are also prospects for using the extract to alleviate colitis (Akkol et al, 2020). Information is available on the impact of rowanberry fruits on protein glycation, a process in which sugar molecules react with proteins, causing them to form cross-links and lose functionality, leading to what is known as glycation or "sweet ageing" ( Boiarska, 2019). Therefore, as noted by M. Rutkowska et al (2019), organic compounds in Sorbus aucuparia L. fruits in the form of fractionated extracts inhibit glycation or the protein glycation process and oxidative/nitrative damage to human plasma components.…”

Section: Discussionmentioning

confidence: 99%

Morpho-physiological characteristics of plants and biochemical parameters of rowan berries, common rowan, and domestic rowan grown in the conditions of the Northern Forest-Steppe of Ukraine

Moskalets,

Hulko,

Rozhko

et al. 2023

Scientific Horizons

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The relevance of this subject lies in the comparative evaluation of different species of rowan to increase their significance and use in the system of ornamental and fruit horticulture, in the technologies of processing plant raw materials, and in the production of products for healthy nutrition. The purpose of the study is to examine the morpho-physiological characteristics of plants and the biochemical parameters of the fruits of different species (varieties, forms) of the genus Sorbus. Based on the results of practical research, original data on the morphology and economic characteristics of representatives (varieties and forms) of Sorbus intermedia Pers., Sorbus aucuparia L., Sorbus domestica L. are presented. Biological properties of the plants and biochemical parameters of the fruits are highlighted. It is established that all studied representatives of the genus Sorbus have high winter hardiness (1.5 points according to S.Ya. Sokolova), in addition, Scandinavian rowan plants have high drought resistance (4.5 points according to S.S. Pyatnitsky) compared to common rowan plants. Phenological observations of plants of different rowan species allowed for the conditions of the Forest-Steppe of Ukraine to determine the time of onset of ontogenesis phases: development of vegetative buds, appearance of leaves, shoot growth, budding, and flowering, formation and development of ovaries, ripening and fruiting, changes in leaf colour, and leaf fall. Subphases that more accurately characterise the time of onset, peak, and end of a certain phase of development have also been identified, which is a scientific achievement for strategies in the system of ornamental and fruit horticulture. The growth intensity of varieties and forms of representatives of the Sorbus genus in height was studied, and the general condition of plants for viability is evaluated. Preparatory work on the preparation of rootstocks, the selection of scions, and grafting allowed the formation of model plants in the collection nursery and additional assessment of their growth strength, the onset and passage of individual phases of development, assessment of drought and winter hardiness, age of fruiting, and more. Biometrics and descriptions of stem, branches, vegetative and generative buds, leaves, inflorescences, and fruits are also conducted. The taste characteristics of the fruits are described in the materials of the paper. Biochemical analysis of the fruits allowed establishing their suitability for processing and the production of products for healthy nutrition

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Section: Discussionmentioning

confidence: 99%

Morpho-physiological characteristics of plants and biochemical parameters of rowan berries, common rowan, and domestic rowan grown in the conditions of the Northern Forest-Steppe of Ukraine

Moskalets,

Hulko,

Rozhko

et al. 2023

Scientific Horizons

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Leukocytes in type 1 diabetes mellitus: the changes they undergo and induce

Kuchurka¹,

Chaban²,

Dzydzan³

et al. 2022

Biol. Stud.

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As leukocytes represent cellular and humoral immunity at the same time, they are a vital part of every immune process. This also stands for autoimmune processes and disorders, such as diabetes, specifically type 1 diabetes mellitus. Diabetes mellitus is one of the most widespread autoimmune diseases. Development of type 1 diabetes mellitus is mediated through complicated mechanisms of intercellular communication where leukocytes function as the key element, being both effectors and regulators. However, the immunocompetent cells are also affected by diabetic alterations, powered by chronic hyperglycemia. For example, the products of non-enzymatic interaction of glucose or other reducing sugars with either proteins or lipids, called advanced glycation end products, are associated with the development of long-term negative changes in diabetes. By binding to the receptors for advanced glycation end-products, they trigger the signaling pathways involved in expression of pro-inflammatory genes, which results in diabetic complications. As long as diabetes mellitus remains a global healthcare issue and several details of its pathogenesis are still to be discovered, it is important to analyze and investigate the peculiarities of alterations in leukocytes under type 1 diabetes mellitus, particularly the ones caused by advanced glycation end-products and their receptors.

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Anti–Glycation Aging Prevention Strategies

Cited by 2 publications

References 37 publications

Morpho-physiological characteristics of plants and biochemical parameters of rowan berries, common rowan, and domestic rowan grown in the conditions of the Northern Forest-Steppe of Ukraine

Morpho-physiological characteristics of plants and biochemical parameters of rowan berries, common rowan, and domestic rowan grown in the conditions of the Northern Forest-Steppe of Ukraine

Leukocytes in type 1 diabetes mellitus: the changes they undergo and induce

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