Anti-inflammatory Agent

Ashworth, Jason J.

doi:10.1007/978-981-19-5735-2_4

Cited by 2 publications

(1 citation statement)

References 60 publications

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“…Ferulic acid, which is an essential component of rice bran, has been reported to show antineuroinflammatory and neuroprotective activity by reducing the rates of proinflammatory markers like NF‐κB, iNOS, TNF‐α, IL‐6, and COX‐2 and by increasing antioxidant enzymes such as SOD, CAT (Araujo et al, 2015; Behl et al, 2021; Chotimarkorn & Ushio, 2008). Ashworth (2023) also reported that arabinoxylans or arabinoxylans‐derived products of rice bran like feruloylated oligosaccharides and ferulic acid are chiefly responsible for the anti‐inflammatory activity of rice bran. The effect of rice bran oil niosomes of three different varieties has been studied on the expression of varying proinflammatory genes and found that the expression of IL‐1β and TNF‐α genes in the LPS‐stimulated THP‐1 monocytes was reduced (Jom et al, 2021).…”

Section: Fundamental Medicinal Properties Of Rice Branmentioning

confidence: 99%

Recent trends of potential medicinal uses of rice bran with its composition and bibliographic analysis

Kumar

Singh

Sharma

2023

eFood

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Rice is an essential crop, growing in nearly every part worldwide. Grains are the most common rice plant part consumed as food; however, other plant parts also have some significant values apart from grains. Rice bran is the outer layer of the rice grain, an excellent source of various phenolic, flavonoid, and phytoactive compounds. This review article discusses the various compounds found in rice bran with their structure and properties. Different medicinal properties of rice bran are also discussed in this review article. Several constituents of rice bran show anticancerous activity through various mechanisms like cell cycle arrest and regulation of apoptotic factors. Anti‐inflammatory, antidiabetic, antihypertensive, and cholesterol‐lowering are the other activities of rice bran, briefly explained in the article, along with their mechanism of action. A bibliographic network, including keyword bibliography analysis and a three‐field plot, has also been discussed to show the trends and network of common keywords in the recently published documents in the Scopus database. Overall, this review explores the rice bran compositions with their structures, activity, and various medicinal uses of rice bran, which can be proven an efficient oil source for nutritional purposes.

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Section: Fundamental Medicinal Properties Of Rice Branmentioning

confidence: 99%

Recent trends of potential medicinal uses of rice bran with its composition and bibliographic analysis

Kumar

Singh

Sharma

2023

eFood

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Modified rice bran arabinoxylan as a nutraceutical in health and disease—A scoping review with bibliometric analysis

Ooi,

Micalos,

Pak

2023

PLoS ONE

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Rice bran arabinoxylan compound (RBAC) is a polysaccharide modified by Lentinus edodes mycelial enzyme widely used as a nutraceutical. To explore translational research on RBAC, a scoping review was conducted to synthesise research evidence from English (MEDLINE, ProQuest, CENTRAL, Emcare, CINAHL+, Web of Science), Japanese (CiNii, J-Stage), Korean (KCI, RISS, ScienceON), and Chinese (CNKI, Wanfang) sources while combining bibliometrics and network analyses for data visualisation. Searches were conducted between September and October 2022. Ninety-eight articles on RBAC and the biological activities related to human health or disease were included. Research progressed with linear growth (median = 3/year) from 1998 to 2022, predominantly on Biobran MGN-3 (86.73%) and contributed by 289 authors from 100 institutions across 18 countries. Clinical studies constitute 61.1% of recent articles (2018 to 2022). Over 50% of the research was from the USA (29/98, 29.59%) and Japan (22/98, 22.45%). A shifting focus from immuno-cellular activities to human translations over the years was shown via keyword visualisation. Beneficial effects of RBAC include immunomodulation, synergistic anticancer properties, hepatoprotection, antiinflammation, and antioxidation. As an oral supplement taken as an adjuvant during chemoradiotherapy, cancer patients reported reduced side effects and improved quality of life in human studies, indicating RBAC’s impact on the psycho-neuro-immune axis. RBAC has been studied in 17 conditions, including cancer, liver diseases, HIV, allergy, chronic fatigue, gastroenteritis, cold/flu, diabetes, and in healthy participants. Further translational research on the impact on patient and community health is required for the evidence-informed use of RBAC in health and disease.

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Anti-inflammatory Agent

Cited by 2 publications

References 60 publications

Recent trends of potential medicinal uses of rice bran with its composition and bibliographic analysis

Recent trends of potential medicinal uses of rice bran with its composition and bibliographic analysis

Modified rice bran arabinoxylan as a nutraceutical in health and disease—A scoping review with bibliometric analysis

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