Antibacterial activity and bioactive compounds of 50% hydroethanolic extract of Alpinia zerumbet (Pers.) B.L. Burtt &amp; R.M. Sm.

Tavichakorntrakool, Ratree; Lulitanond, Aroonlug; Sangka, Arunnee; Sungkeeree, Seksit; Weerapreeyakul, Natthida

doi:10.4103/2221-1691.259000

Cited by 8 publications

(7 citation statements)

References 5 publications

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“…Alpinia spp. belongs to the ginger family, Zingiberaceae, and its extracts have been found to contain active compounds for therapeutic properties [99], including antioxidant, anti-inflammatory, and anti-microbial activities (Table 3) [100][101][102][103][104][105][106][107][108][109][110][111][112][113]. Effective against food contaminants that cause hepatotoxicity; possesses anti-inflammatory properties [112,113] 5,6-dehydrokawain (DK) and dihydro-5,6-dehydrokawain (DDK), found in the rhizomes and leaves of Alpinia zerumbet, exhibit antioxidant [101] characteristics and pro-foundly inhibit collagenase, elastase, hyaluronidase, and tyrosinase activity [100].…”

Section: Alpinia Spp Extracts and Their Active Compoundsmentioning

confidence: 99%

Phytogenics in Ginger, Origanum vulgare, and Syzygium aromaticum and Their Potential as a Feed Additive against Clostridium perfringens in Broiler Production

Valdez,

Shyur,

Wang

et al. 2023

Animals

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Necrotic enteritis is a devastating disease in chickens mainly caused by Clostridium perfringens—particularly, Net-B toxin-producing strains. In order to combat necrotic enteritis in broiler production, natural growth promoters, as well as anti-inflammatory and non-antibiotic remedies, were developed for anti-microbial resistance due to its status as a global pandemic. Herein, phytogenic ginger, wild marjoram, and cloves were reviewed as potential alternatives to antibiotics for their anti-microbial functions. These phytogenics contain active ingredients that efficiently modulate the immune response and improve intestinal morphology and overall growth performance, even under stress and infection conditions. Most of the beneficial effects can be attributed to their anti-inflammatory functions, primarily the inhibition of the NF-κB and MAPK pathways. Phytogenics and their active ingredients represent potential substitutes for antibiotic growth promoters, further serving as anti-microbial remedies in the treatment of birds with infections.

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Section: Alpinia Spp Extracts and Their Active Compoundsmentioning

confidence: 99%

Phytogenics in Ginger, Origanum vulgare, and Syzygium aromaticum and Their Potential as a Feed Additive against Clostridium perfringens in Broiler Production

Valdez,

Shyur,

Wang

et al. 2023

Animals

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“…The Minimum bactericidal (MBC) concentration and Minimum fungicidal concentration (MFC) tests were conducted as an adjunct to MIC assay 16 . The lowest concentration inhibiting the growth of test pathogens in tubes were transferred on the respective agar plates, Muller Hinton Agar for bacteria and Potato Dextrose agar for fungi.…”

Section: Minimum Bactericidal Concentration (Mbc) and Minimum Fungicimentioning

confidence: 99%

Evaluation of Chemical Composition, Antibacterial, Antifungal, and Cytotoxic Activity of Laurus nobilis L Grown in Saudi Arabia

Rizwana¹,

Kubaisi²,

Al-Meghailaith³

et al. 2019

J Pure Appl Microbiol

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Present study aimed to evaluate the chemical composition, antibacterial, antifungal, and cytotoxic activity of Laurus nobilis grown in Tabuk region of Saudi Arabia. Dried leaves of L. nobilis were extracted with various solvent with increasing polarities. Solvent extracts exhibited variable inhibition zones against bacterial pathogens, however all the solvent extracts showed significant inhibition against fungal pathogens. Acetone extracts had the largest inhibition zone against Streptococcus pnemoniae (37.16 ± 0.23 mm) while ethanol and methanol extract showed the most efficient percentage inhibition against mycelial growth of Alternaria alternata (91.33 ± 0.47; 90.66 ± 0.94).High cytotoxicity was demonstrated by methanol and aqueous extracts (IC50 14.90µg/ml, 24.56 µg/ml), while acetone extracts showed moderate effects on cell inhibition (IC50 41.43µg/ml).The significant activity shown by the bay leaf extracts could be attributed to monoterpene hydrocarbons, oxygenated monoterpenes, phenylpropanoids, phenols, and other important phytoconstituents identified in GC-MS and FTIR studies. Our findings clearly show significant antifungal, antibacterial and cytotoxic activity of solvent extracts of bay leaves, which could be attributed to the presence of wide range of phytochemicals. Since plants derived natural products are less toxic, cheaper, and have negligible side effects, they would serve as an excellent alternative to antimicrobial and chemotherapeutic drugs.

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“…Other ancient records stated that Alpinia zerumbet is effective on warming the middle, drying dampness, regulating Qi, and stopping pain. Some studies revealed that Alpinia zerumbet is rich in a variety of bioactive substances possessing a myriad of physiological activities, including antioxidant, anti‐inflammatory, [1,2] neuroprotective, [3] anticancer, [4] and antibacterial effects [5] . The rich active ingredients of Alpinia zerumbet are mainly composed of dihydro‐5,6‐dehydrokavain and its derivative, [6] EOs, and phenols [7] .…”

Section: Introductionmentioning

confidence: 99%

“…Some studies revealed that Alpinia zerumbet is rich in a variety of bioactive substances possessing a myriad of physiological activities, including antioxidant, anti-inflammatory, [1,2] neuroprotective, [3] anticancer, [4] and antibacterial effects. [5] The rich active ingredients of Alpinia zerumbet are mainly composed of dihydro-5,6-dehydrokavain and its derivative, [6] EOs, and phenols. [7] As regards the EO from Alpinia zerumbet fruits, there is a lack of comparison of EOs obtained by different extraction methods, and scarce systematic studies are available on the antimicrobial and anti-inflammatory activities.…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition and Potential Antimicrobial and Anti‐Inflammatory Activities of Essential Oil from Fruits of Alpinia zerumbet (Pers.) B.L.Burtt & R.M.Sm.

Hou,

Gong,

Gong

et al. 2023

Chemistry & Biodiversity

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Alpinia zerumbet (Pers.) B.L.Burtt & R.M.Sm. was extensively used in traditional medicine for its several properties, but continuous investigation is needed to discover the properties of its essential oils (EOs). This work evaluated the properties of an EO obtained by steam distillation (named ESD) as well as extracts obtained by petroleum ether (named EP) both from Alpinia zerumbet fruits. Gas chromatography‐mass spectrometry (GC‐MS) was chosen to identify the composition, and eleven compounds were identified as the main components of the EO and EP of Alpinia zerumbet fruits. The antimicrobial properties were investigated by minimum inhibitory concentration (MIC) and the inhibition area. The results identified the differences in antimicrobial activities attributed to different extraction methods. Enzyme‐linked immunosorbent assay (ELISA) and Western Blot (WB) assay were conducted to assess the anti‐inflammatory effects of ESD. In conclusion, our study suggested that EO from Alpinia zerumbet fruits might be a prospective candidate for antimicrobial and anti‐inflammatory therapy.

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Antibacterial activity and bioactive compounds of 50% hydroethanolic extract of Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm.

Cited by 8 publications

References 5 publications

Phytogenics in Ginger, Origanum vulgare, and Syzygium aromaticum and Their Potential as a Feed Additive against Clostridium perfringens in Broiler Production

Phytogenics in Ginger, Origanum vulgare, and Syzygium aromaticum and Their Potential as a Feed Additive against Clostridium perfringens in Broiler Production

Evaluation of Chemical Composition, Antibacterial, Antifungal, and Cytotoxic Activity of Laurus nobilis L Grown in Saudi Arabia

Chemical Composition and Potential Antimicrobial and Anti‐Inflammatory Activities of Essential Oil from Fruits of Alpinia zerumbet (Pers.) B.L.Burtt & R.M.Sm.

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