Antibacterial activity and phytochemical screening of some medicinal plants commonly used in Saudi Arabia against selected pathogenic microorganisms

Al-Daihan, Sooad; Al-Faham, Manar; Al-shawi, Nora; Almayman, Rawan; Brnawi, Amal; Zargar, Seema; Bhat, Ramesa Shafi

doi:10.1016/j.jksus.2012.11.003

Cited by 78 publications

(56 citation statements)

References 30 publications

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“…In recent years, antimicrobial properties of medicinal plants are being increasingly reported from different parts of the world (Al-Daihan et al, 2013). In the current study, twentyfour methanolic and aqueous crude extracts derived from different parts of twelve medicinal plant species traditionally used in Egyptian folk medicine belonging to different genera and botanical families.…”

Section: Resultsmentioning

confidence: 99%

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Synergistic Effect of Combined Antibiotic and Methanol Extract of Eucalyptus camaldulensis leaf Against Staphylococcus aureus and Pseudomonas aeruginosa

Reda

El-Zawahry

Omar

2017

Int J Appl Sci Biotechnol

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A total of seventy-five medical specimens were collected from different patients admitted to Zagazig university hospital, Egypt. The selected bacterial isolates were distributed as 45 Gram negative bacterial isolates and 30 Gram positive bacterial isolates. The most effective antibiotic was gentamycin followed by amikacin and nitrofurantoin. The multi-drug resistant (MDR) bacterial isolates were selected and identified to four groups; Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Staphylococcus aureus. The selected isolates were screened for their capability of biofilm, hemolysins, lecithinase and protease production. S. aureus AM23 and P. aeruginosa AM41 were selected as the highest biofilm and degrading enzymes producers. Furthermore, twenty-four methanolic and aqueous crude extracts derived from different medicinal plants in Egypt were screened for their antibacterial activity against both selected MDR strains. Methanolic extract of Eucalyptus camaldulensis leaf showed the greatest effect on the tested bacteria. Also, there was a synergistic effect of combined E. camaldulensis leaf extract and antibiotics (Gentamycin and Ceftriaxone) against tested organisms. Transmission electron microscopy showed changes in cell shapes, size, contents and cell envelop of antimicrobials treated bacterial cells compared to the control. Our findings proved that the leaf extracts of E. camaldulensis had great potential as antimicrobial agents in the treatment of infectious organisms.

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Section: Resultsmentioning

confidence: 99%

“…Then after filtration through 8 layers of muslin cloth and centrifuged at 5000g for 10 min the supernatant was collected and concentrated (in oven at 45ºC) to make the final volume half of the original volume (stock solutions) (Al-Daihan et al,2013).…”

Section: Preparation Of Plant Extractsmentioning

confidence: 99%

Synergistic Effect of Combined Antibiotic and Methanol Extract of Eucalyptus camaldulensis leaf Against Staphylococcus aureus and Pseudomonas aeruginosa

Reda

El-Zawahry

Omar

2017

Int J Appl Sci Biotechnol

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“…The dried powder of the leaves was extracted sequentially 6 by soxhlet apparatus 7 , using different solvents depending upon their polarities like Hexane, Acetone, Methanol and water (Flow chart 1). The extracts were concentrated and freed of solvent under reduced pressure, using rotary evaporator.…”

Section: Extraction Techniquementioning

confidence: 99%

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2016

IJPSR

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Objective:The present work is aimed to screen phytochemicals, in vitro antimicrobial and antioxidant activity of the non polar and polar extracts of Acacia sinuata. Methods: Leaves of Acacia sinuata-were collected, dried and powdered. The powdered material is subjected to soxhlet extraction using various polar to non polar solvents and allowed for evaporation. The crude extracts thus obtained were used for further screening of phytochemicals, in vitro antimicrobial activity and antioxidant activities. Results: Phytochemical evaluation of Acacia sinuata proved that most of the secondary metabolites are extracted in polar solvents than non polar solvent like hexane. All the extracts of the Acacia sinuata possess significant amount of phenols and flavonoids and they also showed antimicrobial and antioxidant activity. Out of all the extracts of Acacia sinuata, methanol extracts showed better antibacterial, antifungal activity and antioxidant activity. Conclusion: The present work concluded that the methanol extract of Acacia sinuata was useful to develop new plant based dugs against various pathogenic bacteria as well as fungal species.

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“…and getting this herbal into herbal remedy depends upon the solubility of these compounds in various solvents [11] . Phytochemical analysis by Jayshree G.V.…”

Section: Discussionmentioning

confidence: 99%

“…Various antibacterial investigations were carried out of the crude extract obtained from leaves of A. recemosus for the screening of antimicrobial potential. Antibacterial activity obtained in Sooad Al-Daihan et al study varied with solvent used for extraction [11] . Sankarnarayan et al reported that ethnolic extract showed the zone of inhibition against E.coli and S.aureus ranging from 16-24 mm and zone of inhibition with chloroform extract against same organism ranging from 16-20 mm [15] .…”

Section: Discussionmentioning

confidence: 99%

Study of antibacterial activity and biochemical analysis of Asparagus racemosus against selected pathogens causing human intestinal disturbances.

2018

IJAPSA

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The present study is based on the investigation of antibacterial activity of aqueous and ethanolic extracts of Asparagus racemosus. The microorganisms used in the study are human intestinal disturbance causing pathogens viz Staphylococcus aureus, Proteus vulgaris and Escherichia coli. The susceptibility of bacterial strains against the two extracts was determined using disk diffusion method. The most susceptible microorganism was E.coli while the least susceptible organisms was P.vulgaris. Highest antibacterial activity was observed with ethanolic extract of Asparagus recemosus against E.coli (10mm) while minimum activity was observed with aqueous extract of Asparagus recemosus against P.vulgaris (1mm). Ethanolic extract of the sample were more effective in comparison to the aqueous extract in inhibiting the growth of pathogens under study. They were less potent when compared with ciprofloxacin used as positive control. Biochemical analysis shows the presence of alkaloid, flavanoids and tannins in both the extracts while steroids were found only in the aqueous extracts of the plant.

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Antibacterial activity and phytochemical screening of some medicinal plants commonly used in Saudi Arabia against selected pathogenic microorganisms

Cited by 78 publications

References 30 publications

Synergistic Effect of Combined Antibiotic and Methanol Extract of Eucalyptus camaldulensis leaf Against Staphylococcus aureus and Pseudomonas aeruginosa

Synergistic Effect of Combined Antibiotic and Methanol Extract of Eucalyptus camaldulensis leaf Against Staphylococcus aureus and Pseudomonas aeruginosa

Untitled

Study of antibacterial activity and biochemical analysis of Asparagus racemosus against selected pathogens causing human intestinal disturbances.

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