Antibacterial and smear layer removal ability of a novel irrigant, QMiX

Stojičić, Sonja; Shen, Ya; Qian, Wei; Johnson, Bradford R.; Haapasalo, Markus

doi:10.1111/j.1365-2591.2011.01985.x

Cited by 208 publications

(270 citation statements)

References 44 publications

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“…18,19,28,35 QMiX was able to open dentinal tubules without causing erosion (Figure 2A). These findings are in agreement with those of previous studies and with the manufacturer.…”

Section: Discussionmentioning

confidence: 99%

“…18,19 QMiX is recommended after the use of sodium hypochlorite (NaOCl) during root canal instrumentation 18,19 and is effective in removing the smear layer. [18][19][20] Therefore, the present study aimed to evaluate the effects of QMiX, 17% EDTA, 10% citric acid (CA), 1% peracetic acid (PA), 2.5% NaOCl (solution control), and distilled water (negative control) on microhardness reduction and erosion of human root canal dentin. The null hypothesis is that no irrigation protocol reduces microhardness or causes erosion in human root canal dentin.…”

Section: Introductionmentioning

confidence: 99%

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Effect of final irrigation protocols on microhardness reduction and erosion of root canal dentin

et al. 2017

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This study aimed to evaluate the effect of final irrigation protocols on microhardness reduction and erosion of root canal dentin. Sixty root canals from mandibular incisors were instrumented and randomly divided into six groups (n = 10) according to the irrigant used: QMiX, 17% EDTA, 10% citric acid (CA), 1% peracetic acid (PA), 2.5% NaOCl (solution control), and distilled water (negative control). The chelating solutions were used to irrigate the canal followed by 2.5% NaOCl as a final flush. After the irrigation protocols, all specimens were rinsed with 10 mL of distilled water to remove any residue of the chemical solutions. Before and after the final irrigation protocols, dentin microhardness was measured with a Knoop indenter. Three indentations were made at 100 µm and 500 µm from the root canal lumen. Afterwards, the specimens were prepared for scanning electron microscopic analysis and the amount of dentin erosion was examined. Wilcoxon and Kruskal-Wallis tests were used to analyze the results with a significance level set at 5%. At 100 µm, all protocols significantly reduced dentin microhardness (p < .05), while at 500 µm, this effect was detected only in the EDTA and QMiX groups (p < .05). CA was the irrigant that caused more extensive erosion in dentinal tubules, followed by PA and EDTA. QMiX opened dentinal tubules, but did not cause dentin erosion. Results suggest that QMiX and 17% EDTA reduced dentin microhardness at a greater depth. Additionally, QMiX did not cause dentin erosion.

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“…18,19,28,35 QMiX was able to open dentinal tubules without causing erosion (Figure 2A). These findings are in agreement with those of previous studies and with the manufacturer.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of final irrigation protocols on microhardness reduction and erosion of root canal dentin

et al. 2017

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“…This is a premixed and ready to use irrigating solution that contains EDTA, chlorhexidine (CHX) and a detergent (cetrimide), with pH slightly above neutral. This irrigant has demonstrated antibacterial activity comparable to NaOCl and superior activity against planktonic and biofilm bacteria compared to 2% CHX and MTAD (13). Contrarily, Ordinola-Zapata et al (21) observed the poor antibacterial activity when QMiX was applied for 5 min on multispecies biofilm from oral microbiota.…”

Section: Discussionmentioning

confidence: 99%

“…The most important requirements for an ideal endodontic irrigant are to have an antibacterial effect and to penetrate deep into the dentinal tubules. In the last few years, new irrigant solutions for smear layer removal with added antimicrobial agents have been developed (12)(13)(14).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Effect and Surface Tension of Some Chelating Solutions with Added Surfactants

2016

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This study assessed the antimicrobial efficacy and surface tension of established irrigating solutions with a new experimental chelating solution in infected dentin tubes. Twenty-five specimens were randomly assigned to each of the irrigating solutions. Twenty specimens were used as negative and positive controls. After 21 days of contamination with E. faecalis, the irrigating solutions MTAD, QMiX and Tetraclean NA were delivered into each infected root canal. The solutions were removed and dentin samples were withdrawn from the root canals with sterile low-speed round burs with increasing ISO diameters. The dentin powder samples obtained with each bur were immediately collected in separate test tubes containing 3 mL of BHI broth. After that, 100 μL from each test tube was cultured on blood agar. The grown colonies were counted and recorded as colony-forming units (CFU). The surface tension of the irrigants was measured using a Cahn DCA-322 Dynamic Contact Angle Analyzer. A Kruskal Wallis nonparametric ANOVA and a Friedman test were used (p<0.05). Tetraclean NA showed lower surface tension and CFU values than MTAD and QMiX. Better antibacterial action and low surface tension were observed for Tetraclean NA, probably due to the improved penetration into the root canal and dentinal tubes

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“…Recently, a new irrigation solution containing ethylenediaminetetraacetic acid (EDTA), chlorhexidine, and a nonspecified detergent has been introduced called QMix 2in1 (Dentsply Tulsa Dental, Tulsa, OK) 7 . Studies have demonstrated that the QMix solution is an antibacterial agent and is able to remove the smear layer 7,8 .…”

Section: Introductionmentioning

confidence: 99%

The Effect of Qmix Solution in the Removal of Calcium Hydroxide From Artificially Created Grooves

KARATAŞ¹,

Arslan²,

UYGUN³

et al. 2018

Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi

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Aim: The current study aimed to evaluate the effectiveness of QMix and EDTA solutions in removing Ca(OH) 2 from root canals. Materials and Methods:Forty-eight mandibular premolar teeth were instrumented by ProTaper Universal instruments. All of the teeth were then fixed in modified Eppendorf vials using a silicone impression material. After the removal of the specimens from the Eppendorf vials the roots were split into two halves longitudinally and standard longitudinal grooves were then created on the dentinal walls at a level of 3 mm below the cementoenamel junction and 3 mm above from the apex of the roots. The Ca(OH) 2 was placed into the grooves and the specimens were then remounted into the silicone impression material. Six groups were formed: Needle-EDTA, Needle-QMix, Ultrasonic-EDTA, Ultrasonic-QMix, Sonic-EDTA and Sonic-QMix. The root halves were separated and digital images of artificially created grooves were obtained with a stereomicroscope at a 25x magnification. The Ca(OH) 2 left on the artificially created grooves were scored using a 4-graded scoring system and the data were statistically analyzed.Results: Needle QMix group removed more Ca(OH) 2 than with the EDTA group at the apical part of the root canal (P < 0.083). Conclusions:When the irrigation was performed by a conventional needle, the QMix solution had better efficiency than EDTA in removing Ca(OH) 2 from the apical part of the root canal. In clinical practice, the QMix solution can be used effectively for the removal of Ca (OH) 2.

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Antibacterial and smear layer removal ability of a novel irrigant, QMiX

Abstract: QMiX and NaOCl were superior to CHX and MTAD under laboratory conditions in killing E. faecalis and plaque bacteria in planktonic and biofilm culture. Ability to remove smear layer by QMiX was comparable to EDTA.

Cited by 208 publications

References 44 publications

Effect of final irrigation protocols on microhardness reduction and erosion of root canal dentin

Effect of final irrigation protocols on microhardness reduction and erosion of root canal dentin

Antimicrobial Effect and Surface Tension of Some Chelating Solutions with Added Surfactants

The Effect of Qmix Solution in the Removal of Calcium Hydroxide From Artificially Created Grooves

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