Antibiotic prophylaxis for hernia repair.

Abstract

Based on the results of this systematic review the administration of antibiotic prophylaxis for elective inguinal hernia repair cannot be universally recommended. Neither can the administration be recommended against when high rates of wound infection are observed.

Use of antibiotic prophylaxis in elective inguinal hernia repair in adults in London and south-east England: a cross-sectional survey

“…Reviewers at the Cochrane Collaboration concluded in 2012 that evidence derived from 17 randomised controlled trials (RCT) regarding the use of antibiotic prophylaxis in inguinal hernia repair both with and without mesh was inconclusive, neither allowing them to encourage nor discourage its use [6]. A separate meta-analysis, also published in 2012, focussed purely on inguinal hernia repair with mesh and included six of the 11 RCTs identified by the Cochrane review.…”

Administration of Perioperative Penicillin Reduces Postoperative Serum Amyloid A Response in Horses Being Castrated Standing

“…Our purpose was to compare inflammatory responses (by measuring SAA) after nonsutured standing castration in horses administered perioperative procaine penicillin and horses not receiving procaine penicillin, with the overall purpose of determining: (1) if bacteria contribute to the inflammatory response after castration, and (2) if perioperative administration of procaine penicillin may be warranted in nonsutured castration performed in standing horses.…”

A national trainee-led audit of inguinal hernia repair in Scotland

“…The use of antibiotic prophylaxis in elective inguinal hernia repair remains a surgical controversy [16]. The Scottish Intercollegiate Guidelines Network (SIGN) guidelines on prophylactic antibiotics do not recommend the use of prophylactic antibiotics in inguinal hernia surgery either with or without mesh for the majority of cases [17].…”