Antibiotics and antiseptics for pressure ulcers

Norman, Gill; Dumville, Jo C; Moore, Zena; Tanner, Judith; Christie, Janice; Goto, Saori

doi:10.1002/14651858.cd011586

Cited by 14 publications

(6 citation statements)

References 58 publications

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“…Longstanding HAPIs are frequently colonized by microorganisms in a biofilm, which may be composed of bacteria, fungi, or other organisms embedded in the underlying wound, preventing the wound from healing (39). Antimicrobial agents, such as antibacterial and antifungal medications, are often used to treat infected HAPIs (40). Furthermore, fungal infections in the critical care setting are often associated with significant morbidity and mortality; Aspergillus pneumonia is reported to have a mortality rate of 25%, with up to 90% in liver transplant recipients (41).…”

Section: Discussionmentioning

confidence: 99%

Dynamic Risk Prediction for Hospital-Acquired Pressure Injury in Adult Critical Care Patients

Shui

Kim

Aribindi

et al. 2021

Critical Care Explorations

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Section: Discussionmentioning

confidence: 99%

Dynamic Risk Prediction for Hospital-Acquired Pressure Injury in Adult Critical Care Patients

Shui

Kim

Aribindi

et al. 2021

Critical Care Explorations

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“…A Cochrane review from 2014 concluded that systemic antibiotic therapy in venous leg ulcer provides no benefits in terms of healing of the ulcer 11 . This applies also for chronic ulcers of different etiology 12 . Accordingly, systemic antibiotic therapies are not required in chronic ulcers in the absence of clinically manifest wound infection.…”

Section: Special Situationsmentioning

confidence: 99%

“…11 This applies also for chronic ulcers of different etiology. 12 Accordingly, systemic antibiotic therapies are not required in chronic ulcers in the absence of clinically manifest wound infection. Chronic wounds are, however, colonized by bacterial pathogens known to form biofilms.…”

Section: Ulcer Surgerymentioning

confidence: 99%

Perioperative antibiotic prophylaxis in skin surgery – Position paper of the Antibiotic Stewardship working group of the German Society for Dermatologic Surgery (DGDC), Part 2: Special indications and situations

Balakirski,

Becker,

Hartmann

et al. 2023

J Deutsche Derma Gesell

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SummaryIn addition to prevention of surgical site infections after skin surgery, perioperative antibiotic prophylaxis (PAP) aims to prevent the occurrence of other postoperative infectious complications, especially bacterial endocarditis and hematogenous joint prosthesis infections. This article discusses specific indications for the use of PAP. For example, patients who have undergone any type of heart valve replacement, including transcatheter valve replacement or use of prosthetic material to correct the heart valve, or patients who have experienced bacterial endocarditis, require PAP during skin surgery on mucosal membranes or ulcerated tumors.The use of PAP in special situations such as secondary wound healing, septic dermatosurgery or ulcer surgery is also presented and discussed in detail in this paper based on the current scientific literature. This paper represents the second part of the position paper of the Antibiotic Stewardship Working Group of the German Society for Dermatologic Surgery (DGDC) and summarizes evidence‐based recommendations for the administration of PAP during skin surgery for special indications and situations. This is particularly important because, as detailed in Part 1 of this position paper, PAP can and usually should be avoided in skin surgery.

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“…Ein Cochrane‐Review aus dem Jahr 2014 kommt zu dem Schluss, dass eine systemische Antibiotikatherapie bei Ulcus cruris venosum keinen Vorteil für Abheilung der Ulcera bringt 11 . Ähnliches gilt für chronische Ulcera anderer Genese 12 . Somit sind systemische Antibiotikatherapien in Abwesenheit einer klinisch manifesten Wundinfektion bei chronischen Ulcera nicht notwendig.…”

Section: Besondere Situationenunclassified

Perioperative Antibiotikaprophylaxe in der Dermatochirurgie – Positionspapier der Arbeitsgruppe Antibiotic Stewardship der Deutschen Gesellschaft für Dermatochirurgie (DGDC), Teil 2: Spezielle Indikationen und Situationen

Balakirski,

Becker,

Hartmann

et al. 2023

J Deutsche Derma Gesell

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ZusammenfassungNeben der Vermeidung postoperativer Wundinfektionen nach dermatochirurgischen Eingriffen hat die perioperative Antibiotikaprophylaxe (PAP) das Ziel, das Auftreten weiterer postoperativer Infektionskomplikationen, insbesondere der bakteriellen Endokarditis oder hämatogener Gelenkprotheseninfektionen, zu verhindern. In der vorliegenden Arbeit werden spezielle Situationen dargestellt, in denen eine PAP notwendig werden kann. So benötigen Patienten nach Herzklappenersatz jeglicher Art, einschließlich Transkatheter‐Klappenersatz oder bei Verwendung von Prothesenmaterial zur Herzklappenkorrektur, oder Patienten nach einer durchgemachten bakteriellen Endokarditis bei zweizeitigen dermatochirurgischen Eingriffen, Eingriffen an der Schleimhaut oder ulzerierten Tumoren eine PAP.Auch die Anwendung einer PAP in speziellen Situationen wie bei sekundärer Wundheilung, septischen dermatochirurgischen Eingriffen oder Ulcus cruris‐Chirurgie werden in dieser Arbeit anhand der aktuellen wissenschaftlichen Literatur ausführlich dargestellt und diskutiert. Die vorliegende Arbeit ist der 2. Teil des Positionspapiers der Arbeitsgruppe Antibiotic Stewardship der Deutschen Gesellschaft für Dermatochirurgie und formuliert evidenzbasierte Empfehlungen für die Verabreichung einer PAP bei dermatochirurgischen Eingriffen bei speziellen Indikationen und Situationen. Dies ist von besonderer Wichtigkeit, da bei dermatochirurgischen Eingriffen, wie im ersten Teil dargelegt, im Regelfall auf eine PAP verzichtet werden kann und sollte.

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Antibiotics and antiseptics for pressure ulcers

Cited by 14 publications

References 58 publications

Dynamic Risk Prediction for Hospital-Acquired Pressure Injury in Adult Critical Care Patients

Dynamic Risk Prediction for Hospital-Acquired Pressure Injury in Adult Critical Care Patients

Perioperative antibiotic prophylaxis in skin surgery – Position paper of the Antibiotic Stewardship working group of the German Society for Dermatologic Surgery (DGDC), Part 2: Special indications and situations

Perioperative Antibiotikaprophylaxe in der Dermatochirurgie – Positionspapier der Arbeitsgruppe Antibiotic Stewardship der Deutschen Gesellschaft für Dermatochirurgie (DGDC), Teil 2: Spezielle Indikationen und Situationen

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