Antibody to Human T-Lymphotropic Virus Type 1 in West-Indian-Born Uk Residents With Spastic Paraparesis

Human T-cell lymphotrophic viruses in patients with multiple sclerosis

“…Our failure to demonstrate serological evidence for exposure to HTLV I and III (HIV) in patients with multiple sclerosis contrasts with the findings of Koprowski et al [5] but is in agreement with more recent results [1,4,7,8]. Although they are regarded as reliable indicators of HTLV exposure in population screening, Koprowski et al [6] suggest that commercial ELISA tests against disrupted virions are insensitive cornOffprint requests to: D. A. S. Compston pared with assays detecting antibody to the major core protein p24 of HTLV I alone because the antibodies are present in low titre, cross-reactive and only present sporadically in the course of the disease.…”

Antenatal survey for the seroprevalence of HTLV-1 infections in the West Midlands, England

“…In the United Kingdom HTLX-1 infection has been described as mainly prevalent in immigrants from Afro-Caribbean countries [12][13][14]. The virus has been found to occur in remarkable intrafamilial clusters [15].…”

Optic Neuritis and Human T-Lymphotropic Virus Type 1-Associated Myelopathy: A Case Report

“…When she had optic neuritis, the gait disturbance and sphincter impairment had already improved, and the symptoms abated except for slight numbness of the lower extremities. Although there have been several reports published on optic atrophy among numerous ocular manifestations in patients with HAM [9], only 2 cases of optic neuritis have been reported [10]. To the best of our knowledge, this is the first detailed case report on optic neuritis in a patient with HAM.…”