Breast cancer is a significant public health challenge, especially in less developed regions like sub-Saharan Africa. This study assessed the awareness of breast cancer among pregnant women attending antenatal care services at Hoima Regional Referral Hospital in Western Uganda. A total of 200 participants were involved in this cross-sectional study. The results showed that 86% of the participants had heard about breast cancer, while 14% had never heard of it. Factors like age, level of education, religion, and occupation were found to influence awareness levels. However, most women had insufficient knowledge about breast cancer risk factors. This study highlights the need for intensified health education programs and the decentralization of breast cancer screening services to improve awareness and early detection. Keywords: Breast cancer, cancer mortality, Antenatal care services, Women, Mammography.