Anticholinergic agents result in weaker and shorter suppression of uterine contractility compared with intestinal motion: time course observation with cine MRI

Abstract

Suppression of uterine peristalsis was weaker and shorter compared with the stronger and longer suppression of intestinal movement by the intravenous administration of anticholinergic agents.

MR imaging of uterine morphology and dynamic changes during lactation

“…Lactating women were recruited between October 2010 and March 2012, and nulliparous volunteers were recruited between December 2007 and March 2012. A part of nulliparous volunteers also participated in a prior study . In total, 38 healthy women (22 women in the lactation group, 16 women in the control group) were recruited for the study.…”

“…The degree of endometrial transformation, subendometrial conduction, OM conduction, and sporadic myometrial contraction were evaluated on a five‐point grading scale: 0, not present; 1, present, but weak; 2, mild; 3, moderate; and 4, marked. Endometrial transformation was defined as subtle wavelike configurations with or without identifiable direction . Subendometrial conduction was defined as conduction of low signal intensity within the subendometrial myometrium with or without identifiable direction .…”

“…A part of nulliparous volunteers also participated in a prior study. 9 In total, 38 healthy women (22 women in the lactation group, 16 women in the control group) were recruited for the study. The exclusion criteria were: use of oral contraceptive pills (OCs), insertion of intrauterine contraceptive devices (IUD), or known m€ ullerian duct anomalies, because the use of OCs and IUD is indeed known to affect uterine peristalsis.…”

“…5,9 Subendometrial conduction was defined as conduction of low signal intensity within the subendometrial myometrium with or without identifiable direction. 5,9 OM conduction was defined as the conduction of low signal intensity toward the outer myometrium. 9 Myometrial contraction was defined as transient focal masses of low signal intensity on T2WI, bulging into the endometrium.…”

“…5,9 OM conduction was defined as the conduction of low signal intensity toward the outer myometrium. 9 Myometrial contraction was defined as transient focal masses of low signal intensity on T2WI, bulging into the endometrium. 13 The qualitative evaluation was carried out in the following manner: two radiologists independently evaluated the images in a random order, and consensus was subsequently reached when the scores were not in complete agreement.…”