Anticoagulant rodenticides

Murphy, Michael J.

doi:10.1016/b978-0-12-385926-6.00067-3

Cited by 11 publications

(15 citation statements)

References 276 publications

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“…Hemorrhagic lesions observed with anticoagulant pesticides (anemia, hemothorax, hemopericardium) are due to their mechanism of action: they inhibit the recycling of vitamin K1 necessary for the activation of several clotting factors. As a consequence, coagulation is impaired, hence the observed lesions (12, 30). However, contrary to Roch's (12) description, we observed in the 3 cases of anticoagulants' poisoning the presence of a friable blood clot.…”

Section: Discussionmentioning

confidence: 99%

Animal Pesticide Poisoning in Tunisia

et al. 2019

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During the period from 2014 to 2017, a retrospective study on pesticide poisoning in domestic animals and livestock was compiled and then analyzed. A total of 71 pesticide analyses have been submitted to the Pharmacy and Toxicology Laboratory of the School of Veterinary Medicine of Sidi Thabet in Tunisia. All the cases were first referred either through the clinical and/or pathological departments of the Veterinary School, the private and/or governmental veterinarians or directly by the pet owners. Among the total number of the suspected samples, 21 (29.6%) cases were found positive for various kinds of pesticides. Carbamate insecticides were the most frequently implicated pesticide (52.4% of the total positive cases), followed by organophosphate insecticides (19%), then rodenticides-anticoagulants and rodenticides non-anticoagulants (14.3% each). Therefore, carbamates and organophosphates are the most implicated group of pesticides in intoxications (71.4%). Among the 21 positive cases were 11 dogs, 4 cats, 3 poultry, 2 ruminants, and 1 case of bee poisoning. Partition chromatography (HPLC) has been used to characterize the incriminated pesticides. The aim of this survey was to determine incidence and characteristics of pesticide poisoning in domestic and farm animals in Tunisia. The reported results are useful for epidemiological cartography and medical management of intoxicated animals.

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Section: Discussionmentioning

confidence: 99%

Animal Pesticide Poisoning in Tunisia

et al. 2019

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“…in adults, 5-10 mg in children (Greeff et al, 1987), and 2.5-5 mg/kg body weight in animals. A large daily maintenance dose of vitamin K 1 may be required for prolonged therapy in severe overdoses, particularly in patients in whom vitamin K 1 absorption is variable (Lipton and Klass, 1984;Hoffman et al, 1988;Ross et al, 1992;Murphy, 2012).…”

Section: Laboratory Monitoringmentioning

confidence: 99%

Superwarfarins

Murphy¹,

Lugo²

2015

Handbook of Toxicology of Chemical Warfare Agents

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“…Związki tej grupy stosowane są do zwalczania szkodników w uprawach rolnych, lasach, w magazynach z żywnością, a także w mieszkaniach. Wśród nich znaleźć można także związki, które swoim działaniem obejmują ekto-i endopasożyty u zwierząt (42). Zaliczamy do nich także pyretroidy, związki najczęściej stosowane w zapobieganiu chorobom przenoszonym przez kleszcze, komary i muchy (43).…”

Section: Insektycydyunclassified

“…Pestycydy są zaangażowane w większą liczbę przypadków narażenia i śmierci zwierząt niż jaka-kolwiek inna kategoria substancji toksycznych (31,42). Nierzadko substancje te używane są celowo do uśmiercania zwierząt, głównie w postaci przynęt, past czy jako dodatek do wody (10,45).…”

Section: Zapobieganie Zatruciomunclassified

Causes of poisoning in companion animals in Europe

Leśniak¹,

Piedra²,

Księżarczyk³

et al. 2021

Medycyna Weterynaryjna

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Domestic dogs live in the same environment as their owners and are exposed to the same environmental risk factors. For this reason, these animals can serve as indicators of diseases affecting humans. According to epidemiological studies performed by the National Center for Poison Control (NAPCC) in the United States, dogs are a kind of indicator of human exposure to environmental toxins, such as insecticides and herbicides, because they respond to most poisonings analogously to humans. Pesticides, such as rodenticides, insecticides, molluscicides and herbicides, are the most common cause of poisoning in companion animals in Europe. In most species, pesticides are one of the main causes of poisoning. The incidence of pesticide poisoning is significantly dependent on the toxicity of commercial preparations. A ban on the use of

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Anticoagulant rodenticides

Cited by 11 publications

References 276 publications

Animal Pesticide Poisoning in Tunisia

Animal Pesticide Poisoning in Tunisia

Superwarfarins

Causes of poisoning in companion animals in Europe

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