Antiepileptic Drugs

1999

DOI: 10.1007/978-3-642-60072-2_22

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Anticonvulsant Combinations and Interactions

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Antiepileptik Ve Antidepresan İlaçların Birlikte Kullanımı1

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Cited by 5 publications

(1 citation statement)

References 68 publications

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“…Farmakokinetik etkileşimler, ilacın emilim, dağılım, biyotransformasyon ve atılım gibi çeşitli aşamalarında meydana gelebilir. Bunlardan biyotransformasyon genellikle aynı metabolik yolak ve mikrozomal sitokrom P450 oksidaz (CYP) aktivitesinin inhibisyon veya indüksiyonunun rekabetinden en fazla etkilenenidir [75,76]. CYP sistemi üç ana grup ve beş alt gruba ayrılır.…”

Section: Antiepileptik Ve Antidepresan İlaçların Birlikte Kullanımıunclassified

Use of Antidepressants in Epileptic Patients

2013

Ann Clin Anal Med

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No abstract

“…Farmakokinetik etkileşimler, ilacın emilim, dağılım, biyotransformasyon ve atılım gibi çeşitli aşamalarında meydana gelebilir. Bunlardan biyotransformasyon genellikle aynı metabolik yolak ve mikrozomal sitokrom P450 oksidaz (CYP) aktivitesinin inhibisyon veya indüksiyonunun rekabetinden en fazla etkilenenidir [75,76]. CYP sistemi üç ana grup ve beş alt gruba ayrılır.…”

Section: Antiepileptik Ve Antidepresan İlaçların Birlikte Kullanımıunclassified

Use of Antidepressants in Epileptic Patients

2013

Ann Clin Anal Med

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No abstract

Concomitant use of mirtazapine and phenytoin: a drug-drug interaction study in healthy male subjects

et al. 2002

European Journal of Clinical Pharmacology

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Co-administration of mirtazapine did not alter the steady-state pharmacokinetics of phenytoin. The addition of phenytoin to an existing daily administration of mirtazapine results in a decrease of the plasma concentrations of mirtazapine by 46% on average, most likely due to induction of CYP 3A3/4.

Pharmacotherapy of epilepsy: New armamentarium, new issues

¹

2007

Journal of Clinical Neuroscience

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No abstract

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