Antimicrobial Activity Against Bacteria with Dermatological Relevance and Skin Tolerance of the Essential Oil from Coriandrum sativum L. Fruits

Abstract

The aim of this work was to determine the antibacterial activity of essential coriander oil (ECO) on bacteria with dermatological relevance and to assess the skin tolerance of antimicrobial effective ECO concentrations. Essential coriander oil was tested on clinical isolates of different bacteria species, all of which may cause superficial skin infections. Antimicrobial susceptibility testing was performed using a standardized macrodilution test. Essential coriander oil showed good antibacterial activity towards the majority of the bacterial strains tested, including Streptococcus pyogenes (Lancefield group A) and methicillin resistant Staphylococcus aureus (MRSA), with mean minimal inhibitory concentrations of 0.04% v/v and 0.25% v/v, respectively. The skin tolerance of a cream and a lotion containing 0.5% and 1.0% ECO was assessed in 40 healthy volunteers using the occlusive patch test. No skin irritation could be observed by sensitive photometric assessment in any of the volunteers. Because of its activity against Streptococcus pyogenes, Staphylococcus aureus and MRSA combined with excellent skin tolerance, ECO might be useful as an antiseptic for the prevention and treatment of skin infections with Gram-positive bacteria.

Smart Dressings Based on Nanostructured Fibers Containing Natural Origin Antimicrobial, Anti-Inflammatory, and Regenerative Compounds

“…As we mentioned in the previous section, it was already demonstrated that some naturally occurring molecules have antimicrobial [137,151,153], anti-inflammatory [164,166,167] and regenerative properties [172,173,174,175,176,177,178]. From a fabrication point of view, besides the advantages already mentioned of these natural origin materials over antibiotics, their hydrophobicity allows an efficient combination with polymeric matrices often used as wound dressings [189].…”

“…Essential coriander oil was very efficient as an antiseptic for the prevention and treatment of skin infections with Gram-positive bacteria ( Streptococcus pyogenes , S. aureus and MRSA) [153]. In addition, no skin irritation could be observed by sensitive photometric assessment in any of the 40 volunteers using patches impregnated with this essential oil.…”

Medicinal plants with antimicrobial activities (part 2): Plant based review

“…No skin irritation could be observed by sensitive photometric assessment in any of the volunteers. The authors suggested that, because of its activity against Streptococcus pyogenes, Staphylococcus aureus and MRSA, with excellent skin tolerance, ECO might be useful as an antiseptic for the prevention and treatment of skin infections with Gram-positive bacteria [172].…”

Antiradical properties of essential oils and extracts from coriander, cardamom, white, red, and black peppers

“…The seeds contain 1-2% of essential oil, which gives them flavor. Coriander EO is used as antiseptic for leather treatment against bacteria and fungi and to produce flavorings for meat products [28][29][30].…”