Antimicrobial Activity and Characteristics of Asparagus Cochinchinensis Fermented With Lactic Acid Bacteria

Abstract

Asparagus Cochinchinensis is known to ameliorate respiratory disease. We evaluated the antimicrobial activity of non-fermented and fermented A. cochinchinensis using lactic acid bacteria and investigated the physicochemical characteristics of the fermented A.cochinchinensis. Non-fermented A.cochinchinensis showed lower levels of antimicrobial activity than the fermented A.cochinchinensis. Ethyl acetate (EtOAc) extracts of the fermented A. cochinchinensis showed antimicrobial activities against the indicator strains at lower minimum inhibitory concentration (MIC). The MIC of the EtOAc extract of non-fermented A. cochinchinensis against Escherichia coli, Staphylococcus epidermidis, and Stphylococcus aureus were 100, 75, and 100 mg/ml. In contrast, the MIC of the EtOAc extract of ACLM was 25 mg/mL against E. coli. The MIC of the EtOAc extract of ACLS was 12.5 mg/mL against S.epidermidis, and the MIC of the EtOAc extract ofACLP was 12.5 mg/mL against S.aureus. The viable cell number, pH, and acidity of A. cochinchinensis fermented by Lactobacillussakei 383 were similar to those of A. cochinchinensis fermented by Leuconostocmesenteroides 4395, but were different from those of A. cochinchinensis fermented by Lactobacillus.plantarum KCCM 11322. These results suggested that the fermented A. cochinchinensis by lactic acid bacteria may be a good candidate for application to ameliorate respiratory disease.

Microorganisms Involved in Natural Fermentation of Asparagus cochinchinensis Roots and Changes in Efficacies after Fermentation

“…데, 유산균 발효 후 천문동의 항균활성이 개선되어 호흡기 질환에 대한 개선 효과를 보였다 18) . 그리고 Weissella cibaria 로 발효한 천문동은 LPS로 유발된 염증반응을 억제하여 항 천식 효과 19) 및 히알루론산분해효소 억제 효과를 20) , Aspergillus oryzae와 함께 발효한 천문동은 기존의 항산화제보다 더 높 은 환원력과 antityrosinase 활성을 나타내었다 21) .…”

Wound healing effects of Asparagus lucidus Lindl extract through the phosphorylation of ERK1/2

“…In Korea, AL inhabits the southern coastal areas and AL root is used as a traditional medicine. The physiological activity of AL extract has been reported for neuroprotection [ 10 ], anti-inflammation [ 11 ], anti-aging in the brain and liver [ 12 ], anti-oxidation [ 13 ], inhibition of apoptosis [ 14 ], and anti-bacterial activity [ 15 ]. AL extract also has benefits for the skin, such as soothing and reducing inflammation and irritation [ 16 , 17 ].…”