Antimicrobial activity of bioactive compounds and leaf extracts in Jatropha tanjorensis

Viswanathan, M. B.; Ananthi, Jesu Doss Jeya; Perumal, Sathish Kumar

doi:10.1016/j.fitote.2012.07.007

Cited by 30 publications

(23 citation statements)

References 8 publications

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“…Literature also showed that polar solvent extracts (Methanol and chloroform) have antimicrobial active substances [31]. The results observed in this investigation demonstrate that ethanol and methanol extract of J. glauca may contain antimicrobial active substances with antibacterial and antifungal potential.…”

Section: Resultssupporting

confidence: 63%

In vitro Antimicrobial Efficiency of Crude Extracts of Wild Jatropha glauca Plant Leaves Grown Naturally at Al-Baha Region, KSA

Alam¹,

Zabin²,

Nazreen³

2018

WJOC

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The crude extracts from leaves of Jatropha glauca plant grown naturally at Al-Baha region obtained by extraction with ethanol and fractionated using three solvents: petroleum ether, ethyl acetate and methanol were investigated for their in vitro antimicrobial susceptibility. The antimicrobial activity were evaluated against two bacterial strains S. aureus and E. coli, and two common fungal strains Candida albicans and Candida krusei using disc diffusion assay. The crude ethanolic extract and its fractions methanolic and ethyl acetate showed an inhibitory effect against both bacterial and fungal microorganisms. The petroleum ether fraction had no antimicrobial effect. The ethanolic crude extract and methanolic fraction showed higher zone of inhibition, while the ethyl acetate fraction showed the least activity against both bacterial strains. The methanolic fraction was found to possess lowest MIC ≥250 μgml −1 against both tested bacterial strains. Similarly, the ethanolic crude extract and methanol fraction showed zone of inhibition against tested fungal strains with methanolic fraction showed the highest zone of inhibition. However, these observations indicated that the ethanolic crude extract and its methanolic and ethyl acetate fractions exhibited some antimicrobial potency that proves the leaves contain some gradients that have antibacterial and antifungal potential.

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Section: Resultssupporting

confidence: 63%

In vitro Antimicrobial Efficiency of Crude Extracts of Wild Jatropha glauca Plant Leaves Grown Naturally at Al-Baha Region, KSA

Alam¹,

Zabin²,

Nazreen³

2018

WJOC

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“…Plants, specifically medicinal plants, are widely used in medicine and pharmacological sciences. These medicinal plants contain some organic compounds such as polyphenols, aliphatic compounds and peptides which have antimicrobial properties (4)(5)(6)(7)(8)(9)(10). Medicinal herbs have antibacterial compounds which are effective in the treatment of diseases (11)(12)(13)(14)(15)(16)(17).…”

Section: Introductionmentioning

confidence: 99%

In Vitro Study to Evaluate Antibacterial and Non-hemolytic Activities of Four Iranian Medicinal Plants

Sepahi¹,

Ghorani‐Azam²,

Asoodeh³

et al. 2014

West Indian Med J

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“…Table 1 shows the identification of the studied plants, by scientific and common name, traditional use, parts analyzed, and the ethnic group that uses them as medicinal remedy. The extraction method was chosen based on the consideration that methanolic extracts may contain a wide range of chemical compounds with biological activity such as terpenoids, phenols, flavonoids, saponines, steroids, and others [17-20]. In addition, some studies have reported that methanolic extracts are more active than aqueous extracts in their antibacterial activity [21].…”

Section: Resultsmentioning

confidence: 99%

In vitro anti-mycobacterial activity of nine medicinal plants used by ethnic groups in Sonora, Mexico

Robles‐Zepeda

Coronado-Aceves

Velázquez-Contreras

et al. 2013

BMC Complement Altern Med

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BackgroundSonoran ethnic groups (Yaquis, Mayos, Seris, Guarijíos, Pimas, Kikapúes and Pápagos) use mainly herbal based preparations as their first line of medicinal treatment. Among the plants used are those with anti-tuberculosis properties; however, no formal research is available.MethodsOrganic extracts were obtained from nine medicinal plants traditionally used by Sonoran ethnic groups to treat different kinds of diseases; three of them are mainly used to treat tuberculosis. All of the extracts were tested against Mycobacterium tuberculosis H37Rv using the Alamar Blue redox bioassay.ResultsMethanolic extracts from Ambrosia confertiflora, Ambrosia ambrosioides and Guaiacum coulteri showed minimal inhibitory concentration (MIC) values of 200, 790 and 1000 μg/mL, respectively, whereas no effect was observed with the rest of the methanolic extracts at the concentrations tested. Chloroform, dichloromethane, and ethyl acetate extracts from Ambrosia confertiflora showed a MIC of 90, 120 and 160 μg/mL, respectively.ConclusionsA. confertiflora and A. ambrosioides showed the best anti-mycobacterial activity in vitro. The activity of Guaiacum coulteri is consistent with the traditional use by Sonoran ethnic groups as anti-tuberculosis agent.For these reasons, it is important to investigate a broader spectrum of medicinal plants in order to find compounds active against Mycobacterium tuberculosis.

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Antimicrobial activity of bioactive compounds and leaf extracts in Jatropha tanjorensis

Cited by 30 publications

References 8 publications

<i>In</i><i> </i><i>vitro</i> Antimicrobial Efficiency of Crude Extracts of Wild<i> </i><i>Jatropha</i><i> </i><i>glauca</i> Plant Leaves Grown Naturally at Al-Baha Region, KSA

<i>In</i><i> </i><i>vitro</i> Antimicrobial Efficiency of Crude Extracts of Wild<i> </i><i>Jatropha</i><i> </i><i>glauca</i> Plant Leaves Grown Naturally at Al-Baha Region, KSA

In Vitro Study to Evaluate Antibacterial and Non-hemolytic Activities of Four Iranian Medicinal Plants

In vitro anti-mycobacterial activity of nine medicinal plants used by ethnic groups in Sonora, Mexico

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