Antimicrobial Activity of Carbon Nanoparticles Isolated from Natural Sources against Pathogenic Gram-Negative and Gram-Positive Bacteria

Varghese, Sheena; Kuriakose, Sunny; Jose, Seno

doi:10.1155/2013/457865

Cited by 45 publications

(20 citation statements)

References 14 publications

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“…With the known popularity of carbon for its biocompatibility333, which was also tested and confirmed in case of the turmeric smudge derived NC@TS obtained in our study too, it definitely holds an edge to turmeric smoke. This study confirms that harvesting the NC@TS could lead to safer and effective extension of this age old smudging method to real time drug delivery and pharmaceutical applications.…”

Section: Discussionsupporting

confidence: 78%

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The ethanopharmacological aspect of carbon nanodots in turmeric smoke

Chun

Muthu

Enkhtaivan

et al. 2016

Sci Rep

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Smoke manifested ever since our ancient’s lit fire; today it has evolved to become an environmental concern. However, medicinal smoke is still part of man’s natural remedies, religious and cultural practices too. The Asiatic household practice of burning turmeric rhizomes to relieve nose and chest congestion is a well known yet never scientifically authenticated or studied practice. For the first time we investigate the components of these turmeric smudges, validate their antimicrobial and anticancer properties and their cell compatibility. With smoke there is always nanoparticulate carbon and turmeric smoke is no exception. If so, what is the role of the nano carbon (NC) in the turmeric smudge effect? This study isolated, characterized and exposed these secret natural NC undercover agents in turmeric smoke. Their unequivocal role in the ethanopharmocological activity of turmeric smudging has been demonstrated. This work opens a new avenue for use of such nano components of smoke for harnessing the ethanopharmacological property of various medicinal smokes, by excluding the smoke factor, through extracting the nano carbon material in them. This is a possibility to realizing the use of such naturally available nanomaterial, as an eco friendly substitute for the notorious anthropogenic nanomaterials.

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Section: Discussionsupporting

confidence: 78%

“…10(f)); they trigger off a cascade of other attacks on the cytoplasm and organelles, resulting in cell death. It is also interesting to note here that Sheena et al 33,. have reported that kitchen soot derived carbon nanoparticles possessed inherent antibacterial property.…”

Section: Discussionsupporting

confidence: 60%

The ethanopharmacological aspect of carbon nanodots in turmeric smoke

Chun

Muthu

Enkhtaivan

et al. 2016

Sci Rep

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“…[39]. The additional peaks detected at 29.47° and 40.78° are attributed to the natural graphene-like carbon present in the ZnO-CuO nanocomposites [42] as carbon is a main phytochemical element in the leaves of the C. gigantea medicinal plant [43,44]. Natural carbon in binary ZnO-CuO nanocomposites could further enhance the synergic effect on antimicrobial activity [45,46].…”

Section: Time-kill Assaymentioning

confidence: 99%

Calcination Temperatures, Compositions and Antimicrobial Properties of Heterostructural ZnO–CuO Nanocomposites from Calotropis Gigantea Targeted for Skin Ulcer Pathogens

Govindasamy

Mydin

Harun

et al. 2020

Preprint

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Abstract An eco-friendly green route is employed for the successful synthesis of heterostructured ZnO-CuO nanocomposites using Calotropis gigantea plant and the investigation of their antimicrobial properties against skin ulcer pathogens. Binary ZnO-CuO nanocomposites prepared at calcination temperature of 300 °C exhibited superior antimicrobial effect on S. aureus, whereas the negative control sample did not show any antibacterial activities. High ZnO nanoparticles of 75 wt.% ZnO-CuO nanocomposites showed zero count of Staphylococcus aureus at a minimum inhibitory concentration of 0.625 mg/mL and minimum bactericidal concentration (MBC) of 2.5 mg/mL. Interestingly, the 75 wt.% ZnO-CuO nanocomposites exhibited strong antimicrobial activity against multi-drug resistant pathogens, with MBC ranging from 0.3125 mg/mL to 1.25 mg/mL. A time-kill assay captured a reduction in viable count from 4.3 log 10 to 1.3 log 10 after 12 h of incubation for S. aureus . Elucidating the antimicrobial activities could be useful for identifying novel ways to incorporate ZnO-CuO nanocomposites in polymers for applications in biocide materials, such as for wound dressing. Further, molecular studies are needed to explain the underlying biocidal mechanism of ZnO-CuO nanocomposites especially in the presence of Cu 2+ and Zn 2+.

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“…Carbon NPs in particular fullerene, carbon nanotubes, graphene and diamond-like carbon structures have been employed for the development of new antimicrobial agents due to the high surface to volume ratio and their unique chemical and physical properties (Varghese et al, 2013). Investigations have revealed that as the size of carbon particles decreases right down to the nanoscale range, their antimicrobial activity will increase due to their larger surface area consistent with unit volume and high percentage of atoms in the surface and near-surface layers.…”

Section: Carbon Nps (C Nps)mentioning

confidence: 99%

“…Investigations have revealed that as the size of carbon particles decreases right down to the nanoscale range, their antimicrobial activity will increase due to their larger surface area consistent with unit volume and high percentage of atoms in the surface and near-surface layers. C NPs have been found to be effective against bacterial strains such as Pseudomonas aeruginosa and S. aureus (Varghese et al, 2013). Also, previous studies demonstrated the antimicrobial properties of singlewalled carbon nanotubes (SWCNT) and multi-walled carbon nanotubes (MWCNT) against different pathogenic bacteria (E. coli, S. epidermidis, B. subtilis, S. aureus) (Kang et al, 2006).…”

Section: Carbon Nps (C Nps)mentioning

confidence: 99%

Nanotechnological approaches for the development of novel antimicrobial strategies

Hussien¹,

Măruţescu²,

Chifiriuc³

2018

Rev. Biol. Biomed. Sci.

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Due to their diverse and multiple antimicrobial features, inorganic and organic nanoparticles (NPs) represent promising candidates for the development of novel antimicrobial strategies, which could be used to complement current antimicrobial agents that fail to combat pathogens, including multidrug-resistant and biofilmforming microorganisms. The high surface / volume ratio of NPs provides a maximum loading of therapeutic molecules. Additionally, NPs coated with different antimicrobial agents could represent an important alternative strategy to combat biofilm infections. Among the most common types of NPs, the metal, metal oxide and carbonbased NPs are the most used for antimicrobial applications and the purpose of this review is to present some of their antimicrobial features.

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Antimicrobial Activity of Carbon Nanoparticles Isolated from Natural Sources against Pathogenic Gram-Negative and Gram-Positive Bacteria

Cited by 45 publications

References 14 publications

The ethanopharmacological aspect of carbon nanodots in turmeric smoke

The ethanopharmacological aspect of carbon nanodots in turmeric smoke

Calcination Temperatures, Compositions and Antimicrobial Properties of Heterostructural ZnO–CuO Nanocomposites from Calotropis Gigantea Targeted for Skin Ulcer Pathogens

Nanotechnological approaches for the development of novel antimicrobial strategies

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