Antimicrobial Peptides: Potential Alternative to Antibiotics and Overcoming Limitations for Future Therapeutic Applications

Somase, Vrushali; Desai, Sharav A.; Patel, Vipul P.; Patil, Vivek; Bhosale, Kunal

doi:10.1007/s10989-024-10623-9

Int J Pept Res Ther

2024

DOI: 10.1007/s10989-024-10623-9

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Antimicrobial Peptides: Potential Alternative to Antibiotics and Overcoming Limitations for Future Therapeutic Applications

Vrushali Somase,

Sharav A. Desai,

Vipul P. Patel

et al.

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Cited by 6 publications

References 206 publications

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Advances in Artificially Designed Antibacterial Active Antimicrobial Peptides

Guo,

Farhan,

Gan

et al. 2024

Biotech & Bioengineering

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Antibacterial resistance has emerged as a significant global concern, necessitating the urgent development of new antibacterial drugs. Antimicrobial peptides (AMPs) are naturally occurring peptides found in various organisms. Coupled with a wide range of antibacterial activity, AMPs are less likely to develop drug resistance and can act as potential agents for treating bacterial infections. However, their characteristics, such as low activity, instability, and toxicity, hinder their clinical application. Consequently, researchers are inclined towards artificial design and optimization based on natural AMPs. This review discusses the research advancements in the field of artificial designing and optimization of various AMPs. Moreover, it highlights various strategies for designing such peptides, aiming to provide valuable insights for developing novel AMPs.

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Advances in Artificially Designed Antibacterial Active Antimicrobial Peptides

Guo,

Farhan,

Gan

et al. 2024

Biotech & Bioengineering

View full text Add to dashboard Cite

show abstract

Thionin Production in Elicited Plant Cell Suspension and its Application as Antibacterial, Anticancer and Anti-Inflammatory Agent

Alharthi,

Althagafi,

Jafri

et al. 2024

Int J Pept Res Ther

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Host Defense Peptides: Exploiting an Innate Immune Component Against Infectious Diseases and Cancer

Adewole,

Oladokun,

Kuku

2024

Int J Pept Res Ther

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Antimicrobial Peptides: Potential Alternative to Antibiotics and Overcoming Limitations for Future Therapeutic Applications

Cited by 6 publications

References 206 publications

Advances in Artificially Designed Antibacterial Active Antimicrobial Peptides

Advances in Artificially Designed Antibacterial Active Antimicrobial Peptides

Thionin Production in Elicited Plant Cell Suspension and its Application as Antibacterial, Anticancer and Anti-Inflammatory Agent

Host Defense Peptides: Exploiting an Innate Immune Component Against Infectious Diseases and Cancer

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