Antimicrobial polymers

Huppmann, T.; Yatsenko, S. O.; Leonhardt, S.; Krampe, Erhard; Radovanovic, I.; Bastian, Martin; Wintermantel, E.

doi:10.1063/1.4873817

Cited by 23 publications

(22 citation statements)

References 3 publications

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“… 264 Recently, coatings of semiconductor-based photocatalysts like TiO 2 over surfaces were studied as antibacterial surfaces and evaluated for the decomposition of various microorganism like bacteria, fungi, and virus. 265 , 266 The decomposition microorganisms principally is due to the light-harvesting ability of TiO 2 . 261 Efficacy of TiO 2 as an antimicrobial agent depends on several parameters: (i) the size and shape of the TiO 2 nanocrystal, (ii) the stability of the TiO 2 nanocrystals (iii) the extent of electron–hole separation, (iv) reduced charge carrier recombination, and (v) the extended absorption in the visible region.…”

Section: Antibacterial and Antiviral Properties Of Nanomaterialsmentioning

confidence: 99%

“…Bulk polymer template was also used by Wintermantel et al for thin-film TiO 2 coating to ensure its surface for antimicrobial application. 266 Different titania content over polymer matrices was studied for antimicrobial activity and found the order 15 wt % > 10 wt % > 2 wt % > 0 wt %. Medical polypropylene coated with nano TiO 2 (21 nm) nanocomposite were prepared via melt compounding in a corotating twin-screw extruder (Berstorff ZE25Ax45D-UTX, Krauss Maffei Berstorff) with an optimized screw configuration.…”

Section: Antibacterial and Antiviral Properties Of Nanomaterialsmentioning

confidence: 99%

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Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Balasubramaniam

Prateek

Ranjan

et al. 2020

ACS Pharmacol. Transl. Sci.

211

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The ongoing worldwide pandemic due to COVID-19 has created awareness toward ensuring best practices to avoid the spread of microorganisms. In this regard, the research on creating a surface which destroys or inhibits the adherence of microbial/viral entities has gained renewed interest. Although many research reports are available on the antibacterial materials or coatings, there is a relatively small amount of data available on the use of antiviral materials. However, with more research geared toward this area, new information is being added to the literature every day. The combination of antibacterial and antiviral chemical entities represents a potentially path-breaking intervention to mitigate the spread of disease-causing agents. In this review, we have surveyed antibacterial and antiviral materials of various classes such as small-molecule organics, synthetic and biodegradable polymers, silver, TiO2, and copper-derived chemicals. The surface protection mechanisms of the materials against the pathogen colonies are discussed in detail, which highlights the key differences that could determine the parameters that would govern the future development of advanced antibacterial and antiviral materials and surfaces.

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Section: Antibacterial and Antiviral Properties Of Nanomaterialsmentioning

confidence: 99%

Section: Antibacterial and Antiviral Properties Of Nanomaterialsmentioning

confidence: 99%

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Balasubramaniam

Prateek

Ranjan

et al. 2020

ACS Pharmacol. Transl. Sci.

211

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“…Ag + can interfere with mammalian cell function through a competitive protein complexation and silver-containing polymers can damage mammalian cells [ 69 , 70 ]. Antimicrobial metal oxides such as zinc and titanium with improved biocompatibility can potentially be used instead of the cytotoxic Ag + [ 120 , 121 , 122 ]. Similarly, halogenated catechol such as chlorocatechols had been demonstrated to be toxic to zebra fish, a model organism [ 123 ].…”

Section: Summary and Future Outlooksmentioning

confidence: 99%

Catechol-Based Antimicrobial Polymers

et al. 2021

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Catechol is a key constituent in mussel adhesive proteins and is responsible for strong adhesive property and crosslinking formation. Plant-based polyphenols are also capable of chemical interactions similar to those of catechol and are inherently antimicrobial. This review reports a series of catechol-based antimicrobial polymers classified according to their antimicrobial mechanisms. Catechol is utilized as a surface anchoring group for adhering monomers and polymers of known antimicrobial properties onto various types of surfaces. Additionally, catechol’s ability to form strong complexes with metal ions and nanoparticles was utilized to sequester these antimicrobial agents into coatings and polymer matrices. During catechol oxidation, reactive oxygen species (ROS) is generated as a byproduct, and the use of the generated ROS for antimicrobial applications was also introduced. Finally, polymers that utilized the innate antimicrobial property of halogenated catechols and polyphenols were reviewed.

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“…Generally, TiO 2 is used as a thin film on surfaces to incorporate an antimicrobial character. The application of TiO 2 nanoparticles incorporated into a medical grade polypropylene matrix results in impact resistant surface characteristics with superior photocatalytic and antibacterial properties of TiO 2 …”

Section: Chemically Modified Polymer To Induce Antimicrobial Activitymentioning

confidence: 99%

Jain

Duvvuri

Farah

et al. 2014

Adv Healthcare Materials

404

302

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Better health is basic requirement of human being, but the rapid growth of harmful pathogens and their serious health effects pose a significant challenge to modern science. Infections by pathogenic microorganisms are of great concern in many fields such as medical devices, drugs, hospital surfaces/furniture, dental restoration, surgery equipment, health care products, and hygienic applications (e.g., water purification systems, textiles, food packaging and storage, major or domestic appliances etc.) Antimicrobial polymers are the materials having the capability to kill/inhibit the growth of microbes on their surface or surrounding environment. Recently, they gained considerable interest for both academic research and industry and were found to be better than their small molecular counterparts in terms of enhanced efficacy, reduced toxicity, minimized environmental problems, resistance, and prolonged lifetime. Hence, efforts have focused on the development of antimicrobial polymers with all desired characters for optimum activity. In this Review, an overview of different antimicrobial polymers, their mechanism of action, factors affecting antimicrobial activity, and application in various fields are given. Recent advances and the current clinical status of these polymers are also discussed.

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Antimicrobial polymers - The antibacterial effect of photoactivated nano titanium dioxide polymer composites

Cited by 23 publications

References 3 publications

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Catechol-Based Antimicrobial Polymers

Antimicrobial Polymers

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