Antimicrobial Properties of Methanol Extract of Dacryodes edulis Seed and Determination of Phytochemical Composition Using FTIR and GCMS

Abstract

Local medicine in some African countries has utilized the plant parts of Dacryodes edulis to treat various ailments such as wounds, skin diseases, dysentery, and fever. Some of these diseases are caused by pathogenic bacteria. To validate the tradomedical applications of D. edulis, an investigation of the phytochemical, antimicrobial properties of the methanol extract of the seed was conducted, Fourier transform infrared spectroscopy (FTIR) and Gas chromatography-mass spectroscopy (GC-MS) analysis was also carried out to determine compounds responsible for these medicinal properties. The Phytochemical screening revealed the presence of Tannins, Phenols, Terpenoids, Flavonoids, Steroids, Phenolic compounds, and Glycosides in the extracts. Results from the antimicrobial screening revealed inhibition was against specific Gram-positive and Gram-negative bacteria and the antimicrobial inhibition properties were acceptable when compared with the standard drug (ciprofloxacin). The Fourier transform infrared spectroscopy (FTIR) spectra showed a variation of the peaks indicating synergy among the functional groups present in the extract. Forty-four (44) peaks were observed in the Gas chromatographymass spectroscopy (GC-MS) spectra and the compounds with the highest percentage concentration where recorded and their medicinal properties correlated with the local utility of the plant's seed extract.

Antioxidant and Antimicrobial Activities of Various Extracts from Safou (Dacryodes edulis) Cultivated in Côte d’Ivoire

“…Methanolic extract of D. edulis had the highest activity against microorganisms tested. This result corroborates with investigations made by [26,27] using methanol as solvents for the extraction.A previous study has indicated greatpotential for the plant in the battle againstmalaria and other diseases [12,28].…”

In-silico molecular studies of the phytochemicals in ethanolic extract of Chromolaena Odorata against H+/K+-ATPase enzyme for Proton Pump inhibitor

“…The leaves were shade-dried at room temperature, and powdered with mortar and pestle kept in an amber colour container prior to analysis. 26…”

Synthesis and Structural Characterisation of Some Carbohydrate Steroid Hybrids

“…Glycosteroids form an interesting family of biomolecules widely encountered in Nature, comprising saponins [1][2][3][4][5] and steroid glycosides [6,7], and exhibiting a wide range of biological properties. New types of glycosteroids are continuously discovered [8][9][10][11][12][13] in various vegetals and organisms, and the spectrum of biological properties and relevant therapeutic interest is immense.…”