1985
DOI: 10.1111/j.1748-5827.1985.tb02110.x
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Antimicrobial prophylaxis in canine surgery

Abstract: In 1961, Burke showed that antibiotics affect primary wound infections favourably only if they are administered before or shortly after bacterial contamination. The effect is optimal if there is already an effective tissue concentration at the time of contamination. During surgery the animal's resistance is strongly reduced, and consequently an infection may be caused by an inoculum present in a rather low concentration, at least lower than in normal circumstances. This reduced resistance lasts until only a fe… Show more

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Cited by 6 publications
(1 citation statement)
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“…Prior to the surgery all dogs were kept off feed for 08 hours and a complete clinical examination along with complete blood count was performed on each dog to rule out anaemia which can alter the results by directly affecting wound healing (Slatter 2003;Fossum 2019). Before the surgical procedure, cephalic vein of each dog was catheterized with 22-24 gauge canula (B. Braun, Lahore, Pakistan) (Weidema 1985;Tilley and Smith Jr. 2011) followed by shaving of surgical site (Slatter 2003).…”
Section: Pre-operative Preparationmentioning
confidence: 99%
“…Prior to the surgery all dogs were kept off feed for 08 hours and a complete clinical examination along with complete blood count was performed on each dog to rule out anaemia which can alter the results by directly affecting wound healing (Slatter 2003;Fossum 2019). Before the surgical procedure, cephalic vein of each dog was catheterized with 22-24 gauge canula (B. Braun, Lahore, Pakistan) (Weidema 1985;Tilley and Smith Jr. 2011) followed by shaving of surgical site (Slatter 2003).…”
Section: Pre-operative Preparationmentioning
confidence: 99%