Antimicrobial Prophylaxis in the Age of Emerging Transplant Infections

Hand, Jonathan

doi:10.1007/978-3-030-01751-4_7-1

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Candidate Screening and Recipient Prophylaxis: Prevention Of...1

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2021

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“…Adapted from Husain et al [15 ▪ ], Aslam and Rotstein [16 ▪ ] and Hand [13]. ATG, antithymocyte globulin; CMV, cytomegalovirus; MELD, model for end-stage liver disease; TMP-SMX, trimethoprim-sulfamethoxazole.aTMP-SMX is preferred.…”

Section: Candidate Screening and Recipient Prophylaxis: Prevention Of...mentioning

confidence: 99%

Prevention of infection and optimizing vaccination in the solid organ transplant candidate and recipient

Ryu

Narayanan

Bhatt

2021

Current Opinion in Organ Transplantation

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Purpose of review Infections can result in serious complications in solid organ transplant (SOT) patients. The need to remain up to date on recommendations on screening, vaccinations, and chemoprophylaxis is paramount in the management of SOT patients. The goal of this review is to provide an overview of current recommendations for the prevention of infections and optimization of vaccinations from the pretransplant through posttransplant periods. Recent findings There is an emphasis on thorough pretransplant evaluation to guide clinicians and pretransplant testing based on epidemiological and endemic risk factors. Additionally, recent studies on vaccine safety and efficacy of newer vaccine formulations in SOT recipients are addressed. Summary This review provides insight on updated recommendations for pretransplant screening, new data on vaccine optimization in SOT recipients and posttransplant prophylaxis. Further research is needed in order to improve preventive measures including screening tests, vaccines, and chemoprophylaxis.

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