Antimicrobial screening and effect of the pulp extracts of &lt;i&gt;Zizyphus spina-christi&lt;/i&gt; (Linnaeus Desf) on some biochemical parameters in rats

Tom, Garba M; Yesufu, Hassan B.; Abdulrahman, F. I.

doi:10.4314/jpb.v6i2.63329

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The extract showed MIC of 6.25 mg/ml against E. coli and C. albicans. The minimum bactericidal concentration of the pulp aqueous extract was 12.5mg/ml for Streptococcus pyogenes (Tom et al, 2009). Methanol extract of Z. spina-christi roots showed antifungal activity against dermatophytes, including Trichophyton rubrum, T. mentagaphytes, Microsporum canis and Aspergillus fumigatus (Adamu et al, 2006).…”

Section: Antibacterial and Antifungal Propertiesmentioning

confidence: 99%

Phytochemistry and pharmacologic properties of Ziziphus spina christi (L.) Willd.

Asgarpanah

Haghighat²

2012

Afr. J. Pharm. Pharmacol.

View full text Add to dashboard Cite

Ziziphus spina-christi known as Christ's Thorn Jujube, is a native plant that grows in tropical and subtropical regions especially in Middle East. Its extracts are important in drug development with pharmacological activities in the Middle East and South and East of Asia including Iran. For a long time, Z. spina-christi has been used in alternative medicine for the treatment of fever, pain, dandruff, wounds and ulcers, inflammatory conditions, asthma and to cure eye diseases. Z. spina-christi has recently been shown to have antibacterial, antifungal, antioxidant, anti-hyperglycemic, and antinociceptive activities. Flavonoids, alkaloids and saponins are the main phytochemicals that are reported from this plant. Geranyl acetone, methyl hexadecanoate, methyl octadecanoate, farnesyl acetone C, hexadecanol and ethyl octadecanoate are characterized as the major components of the leaves' volatile oil. Due to the easy collection of the plant materials, its being cheap and widespread in many countries and also remarkable biological activities, this plant has become both medicine and food in some parts of the world, especially throughout the Middle East including Iran. This paper presents comprehensive analyzed information on the botanical, chemical and pharmacological aspects of Z. spina-christi.

show abstract

Section: Antibacterial and Antifungal Propertiesmentioning

confidence: 99%

Phytochemistry and pharmacologic properties of Ziziphus spina christi (L.) Willd.

Asgarpanah

Haghighat²

2012

Afr. J. Pharm. Pharmacol.

View full text Add to dashboard Cite

show abstract

“…Actually, varied results of antibacterial and antifungal activity of the fruit of Ziziphus spina-christi were published. Tom et al, (2009) cited that the aqueous extract of the pulp (fruit) of Ziziphus spina-christi has antibacterial potential against Escherichia coli, Pseudomonas aeruginosa (Gram-negatives) and antifungal potency against Candida albicans. While, our study showed no effect against Escherichia coli (Ali et al, 2015) mentioned that methanol extract of Ziziphus spina-christi has no antifungal effects against either Aspergillus niger or Candida albicans.…”

Section: Resultsmentioning

confidence: 99%

Antibacterial Activity of Fruit Methanol Extract of Ziziphus spina-christi from Sudan

Abdallah¹

2017

Int.J.Curr.Microbiol.App.Sci

View full text Add to dashboard Cite

Ethnopharmacology, Biological Evaluation, and Chemical Composition of Ziziphus spina-christi (L.) Desf.: A Review

Abdulrahman

Zakariya

Hama

et al. 2022

Advances in Pharmacological and Pharmaceutical Sciences

View full text Add to dashboard Cite

Medicinal plants are the primary raw materials used in the production of medicinal products all over the world. As a result, more study on plants with therapeutic potential is required. The tropical tree Ziziphus spina belongs to the Rhamnaceae family. Biological reports and traditional applications including management of diabetes and treatment of malaria, digestive issues, typhoid, liver complaints, weakness, skin infections, urinary disorders, obesity, diarrhoea, and sleeplessness have all been treated with different parts of Z. spina all over the globe. The plant is identified as a rich source of diverse chemical compounds. This study is a comprehensive yet detailed review of Z. spina based on major findings from around the world regarding ethnopharmacology, biological evaluation, and chemical composition. Scopus, Web of Science, BioMed Central, ScienceDirect, PubMed, Springer Link, and Google Scholar were searched to find published articles. From the 186 research articles reviewed, we revealed the leaf extract to be significant against free radicals, microbes, parasites, inflammation-related cases, obesity, and cancer. Chemically, polyphenols/flavonoids were the most reported compounds with a composition of 66 compounds out of the total 193 compounds reported from different parts of the plant. However, the safety and efficacy of Z. spina have not been wholly assessed in humans, and further well-designed clinical trials are needed to corroborate preclinical findings. The mechanism of action of the leaf extract should be examined. The standard dose and safety of the leaf should be established.

show abstract

Antimicrobial screening and effect of the pulp extracts of <i>Zizyphus spina-christi</i> (Linnaeus Desf) on some biochemical parameters in rats

Cited by 3 publications

References 0 publications

Phytochemistry and pharmacologic properties of Ziziphus spina christi (L.) Willd.

Phytochemistry and pharmacologic properties of Ziziphus spina christi (L.) Willd.

Antibacterial Activity of Fruit Methanol Extract of Ziziphus spina-christi from Sudan

Ethnopharmacology, Biological Evaluation, and Chemical Composition of Ziziphus spina-christi (L.) Desf.: A Review

Contact Info

Product

Resources

About