Antimicrobial susceptibility of Escherichia coli isolates from dairy farms using organic versus conventional production methods

Satô, Kenji; Bartlett, Paul C.; Saeed, Mahdi

doi:10.2460/javma.2005.226.589

Cited by 77 publications

(69 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While it is impossible, from our data, to estimate selection coefficients for different antibiotic resistance traits, the difference in proportion of resistance from human and animal isolates is consistent with a higher degree of selection in the human population. It is also notable that the E. coli collected from livestock and poultry came from adult-or market-age animals and is generally higher than reported for similar studies in developed countries (Khachatryan et al, 2004;Sato et al, 2005;Cho et al, 2007). …”

Section: Discussionmentioning

confidence: 62%

Escherichia coli from Nigeria exhibit a high prevalence of antibiotic resistance where reliance on antibiotics in poultry production is a potential contributing factor

Nsofor¹,

Olatoye²,

Amosun³

et al. 2013

Afr. J. Microbiol. Res.

View full text Add to dashboard Cite

To assess the prevalence of antibiotic resistance in Nigeria, single Escherichia coli isolates were collected from a geographically diverse panel of fecal samples collected from human clinical and nonclinical donors (n=77), livestock (cattle, swine, and goats) and chickens (n=71 total). There was no difference in the proportion of isolates resistant to ≥1 antibiotics from human clinical and non-clinical samples, but overall, this was significantly higher for human (85.7%) compared to animal (53.5%) isolates (P<0.0001). The average number of resistance phenotypes per isolate was significantly higher for human (5.0), goat (4.0), and poultry (3.4) compared with cattle (2.4) and swine (2.0) (P<0.05). There were 25 different resistance phenotypes with more diversity from animal compared with human isolates. A survey of management practices at 30 poultry farms in the vicinity of Ibadan found that all respondents self-milled feed and most (87.7%) routinely added antibiotics to feed. Tetracyclines were the dominant antibiotics of choice followed by tylosin and gentamicin and some use of chloramphenicol, ciprofloxacin, and enrofloxacin. If this pattern of antibiotic resistance and use is repeated across the different sectors of food-animal production and in multiple developing countries, then trade and travel are likely to disseminate resistance traits to other countries potentially negating local policies that are designed to limit selection for antibiotic resistant bacteria.

show abstract

Section: Discussionmentioning

confidence: 62%

Escherichia coli from Nigeria exhibit a high prevalence of antibiotic resistance where reliance on antibiotics in poultry production is a potential contributing factor

Nsofor¹,

Olatoye²,

Amosun³

et al. 2013

Afr. J. Microbiol. Res.

View full text Add to dashboard Cite

show abstract

“…For example, significantly higher prevalence of multidrugresistant E. coli was found in animals that were supplied antimicrobials in feed as compared with those from organic farms (66). Two studies have demonstrated associations between antimicrobial use and prevalence of resistant bacteria isolated from consumer food products (41, 58).…”

Section: Cross-sectional Studies On Food Contamination With Antimicromentioning

confidence: 99%

Industrial Food Animal Production, Antimicrobial Resistance, and Human Health

Silbergeld

Graham

Price

2008

Annu. Rev. Public Health

545

407

View full text Add to dashboard Cite

Antimicrobial resistance is a major public health crisis, eroding the discovery of antimicrobials and their application to clinical medicine. There is a general lack of knowledge of the importance of agricultural antimicrobial use as a factor in antimicrobial resistance even among experts in medicine and public health. This review focuses on agricultural antimicrobial drug use as a major driver of antimicrobial resistance worldwide for four reasons: It is the largest use of antimicrobials worldwide; much of the use of antimicrobials in agriculture results in subtherapeutic exposures of bacteria; drugs of every important clinical class are utilized in agriculture; and human populations are exposed to antimicrobial-resistant pathogens via consumption of animal products as well as through widespread release into the environment.

show abstract

“…Therefore, an infection in one or two animals is often combated by a blanket treatment with antibiotics of the entire house, which may contain over 10,000 animals (Shea, 2004). The farming practice employed may have some bearing on the antibiotic susceptibility of commensal S. aureus; organic farming may result in fewer resistant bacteria than in conventional farms, due to lower exposure to antibiotics and reduced contact between animals (Halbert et al, 2006;Sato et al, 2005;Tikofsky et al, 2003). There is some contrary evidence (Sato et al, 2004), but the continued use of antibiotics in some of the organic farms studied was a possibility (Busato et al, 2000).…”

Section: B Environmental Reservoirs Of Mrsamentioning

confidence: 99%