Antinociceptive and selected physiological effects of morphine and xylazine on tiletamine-zolazepam anesthesia in llamas

Seddighi, Reza; Elliot, Sarah; Whitlock, Brian K; Egger, Christine; Doherty, Thomas J

doi:10.1111/vaa.12128

Cited by 7 publications

(3 citation statements)

References 13 publications

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“…Butorphanol has been shown to provide somatic analgesia in the llama but has a short half‐life of approximately 15 minutes 4 . The full mu‐opioid agonist morphine has been shown to be antinociceptive in the llama 5 ; however, it is not on the allowed substances list. Since analgesic drugs available for this species are limited and llamas are becoming increasingly popular, the use of LA and associated techniques to provide analgesia are an invaluable tool.…”

Section: Introductionmentioning

confidence: 99%

Transverse abdominal plane block in a llama undergoing midline coeliotomy

Thomson

Deutsch²

2021

Vet Record Case Reports

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A 3‐year‐old llama was presented for management of bilateral ureter obstruction. A general anaesthetic was performed to allow a midline coeliotomy to be undertaken. Due to current legislation, the provision of adequate analgesia can be challenging. The transverse abdominis plane (TAP) block is a locoregional technique that can be used to provide analgesia of the ventral abdominal wall in numerous species. The TAP block was performed in this case to provide intraoperative analgesia using mepivacaine. This is the first time this technique has been described in the llama. Based on intraoperative monitoring, the TAP block appears to provide analgesia intra‐operatively. Due to the degree of damage to the ureters, the llama was euthanised under general anaesthesia, so an assessment of postoperative analgesia provided by the block could not be assessed.

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Section: Introductionmentioning

confidence: 99%

Transverse abdominal plane block in a llama undergoing midline coeliotomy

Thomson

Deutsch²

2021

Vet Record Case Reports

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“…The quality of recovery after tiletamine-zolazepam anesthesia has been reported to be dose-dependent [5,29]. The average dose of tiletamine-zolazepam used in this study was 2.1 ± 0.25 mg/kg, which was higher than the dose used for anesthesia of wood bison (1.5-3 mg/kg) but within the recommended range based on the study for wood bison [5]. However, the quality of recovery can be improved using a balanced anesthesia technique to reduce the dosage of tiletamine-zolazepam.…”

Section: Discussionmentioning

confidence: 99%

“…Tiletamine-zolazepam is a readily available commercial veterinary anesthetic agent in most countries and has been used as a part of safe anesthesia protocol in various animals, including small ruminants [4], camelids [5], and wildlife [6]. Tiletamine and zolazepam are combined in a 1:1 ratio by weight of the base and labeled as Telazol ® (Zoetis, Parispanny, NJ, USA) in North America and Zoletil ® (Zoletil ® ; Virbac, Taipei, Taiwan) in other countries.…”

Section: Introductionmentioning

confidence: 99%

Retrospective Comparison of the Anesthetic Effects of Tiletamine–Zolazepam with Dexmedetomidine and Ketamine with Dexmedetomidine in Captive Formosan Serow (Capricornis swinhoei)

Chang,

Weng,

Lien

et al. 2024

Animals

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Formosan serows are endemic to the mountainous regions of Taiwan. This crossover study aimed to assess and compare the anesthetic induction and recovery using either dexmedetomidine–tiletamine–zolazepam (DZ) or dexmedetomidine–ketamine (DK) by intramuscular injection from a blow-dart in a zoo environment. Ten anesthetic procedures were performed with five adult Formosan serows. Each participant was anesthetized with both combinations at least once with a minimal 12-month washout. The average dosages were 22.6 ± 8.3 µg/kg and 35.8 ± 2.5 µg/kg for dexmedetomidine and 185.6 ± 123.6 and 357.8 ± 25.2 µg/kg for atipamezole for the DZ and DK groups, respectively. The doses of tiletamine–zolazepam and ketamine were 2.1 ± 0.25 mg/kg and 3.6 ± 0.3 mg/kg, respectively, in the DZ and DK groups. All participants were induced within 10 min (median: 8 min for both groups), except one serow in the DK group with an induction time of 22 min. Serows in the DZ group had a lower respiratory rate (p = 0.016) and lower rectal temperature (p = 0.008) than those in the DK group. The quality of recovery was poor for DZ because of paddling, prolonged recovery, and ataxia after antagonism of dexmedetomidine with atipamezole. The induction of anesthesia with dexmedetomidine–tiletamine–zolazepam was uneventful and rapid. However, recovery from this combination was not smooth.

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Standing Sedation and Chemical Restraint

Lin

2022

Farm Animal Anesthesia

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Antinociceptive and selected physiological effects of morphine and xylazine on tiletamine-zolazepam anesthesia in llamas

Cited by 7 publications

References 13 publications

Transverse abdominal plane block in a llama undergoing midline coeliotomy

Transverse abdominal plane block in a llama undergoing midline coeliotomy

Retrospective Comparison of the Anesthetic Effects of Tiletamine–Zolazepam with Dexmedetomidine and Ketamine with Dexmedetomidine in Captive Formosan Serow (Capricornis swinhoei)

Standing Sedation and Chemical Restraint

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