Antinociceptive and smooth muscle contracting activities of the methanolic extract of Cassia tora leaf

Chidume, Florence Chimezie; Kwanashie, Helen O.; Adekeye, J.O.; Wambebe, Charles; Gamaniel, K.

doi:10.1016/s0378-8741(02)00079-x

Cited by 25 publications

(11 citation statements)

References 4 publications

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“…C. singueana is reportedly used during malaria for treatment of pain and fever arising from the disease (Adzu et al, 2003). Antinociceptive and smooth muscle contracting activities has been reported for methanolic extract of Cassia tora leaves (Chidume et al, 2002). Analgesic activity has been demonstrated for ethanolic extract of C. fistula stem bark (Ali et al, 2012).…”

Section: Discussionmentioning

confidence: 99%

Tribal Formulations for Treatment of Pain: A Study of the Bede Community Traditional Medicinal Practitioners of Porabari Village in Dhaka District, Bangladesh

Seraj

Jahan

Chowdhury

et al. 2012

Afr. J. Trad. Compl. Alt. Med.

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The Bedes form one of the largest tribal or indigenous communities in Bangladesh and are popularly known as the boat people or water gypsies because of their preference for living in boats. They travel almost throughout the whole year by boats on the numerous waterways of Bangladesh and earn their livelihood by selling sundry items, performing jugglery acts, catching snakes, and treating village people by the various riversides with their traditional medicinal formulations. Life is hard for the community, and both men and women toil day long. As a result of their strenuous lifestyle, they suffer from various types of pain, and have developed an assortment of formulations for treatment of pain in different parts of the body. Pain is the most common reason for physician consultation in all parts of the world including Bangladesh. Although a number of drugs are available to treat pain, including non-steroidal, steroidal, and narcotic drugs, such drugs usually have side-effects like causing bleeding in the stomach over prolonged use (as in the case of rheumatic pain), or can be addictive. Moreover, pain arising from causes like rheumatism has no proper treatment in allopathic medicine. It was the objective of the present study to document the formulations used by the Bede traditional practitioners for pain treatment, for they claim to have used these formulations over centuries with success. Surveys were conducted among a large Bede community, who reside in boats on the Bangshi River by Porabari village of Savar area in Dhaka district of Bangladesh. Interviews of 30 traditional practitioners were conducted with the help of a semi-structured questionnaire and the guided field-walk method. It was observed that the Bede practitioners used 53 formulations for treatment of various types of pain, the main ingredient of all formulations being medicinal plants. Out of the 53 formulations, 25 were for treatment of rheumatic pain, either exclusively, or along with other types of body pain. A total of 65 plants belonging to 39 families were used in the formulations. The Fabaceae family provided 7 plants followed by the Solanaceae family with 4 plants. 47 out of the 53 formulations were used topically, 5 formulations were orally administered, and 1 formulation had both topical and oral uses. 8 formulations for treatment of rheumatic pain contained Calotropis gigantea, suggesting that the plant has strong potential for further scientific studies leading to discovery of novel efficacious compounds for rheumatic pain treatment.

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Section: Discussionmentioning

confidence: 99%

Tribal Formulations for Treatment of Pain: A Study of the Bede Community Traditional Medicinal Practitioners of Porabari Village in Dhaka District, Bangladesh

Seraj

Jahan

Chowdhury

et al. 2012

Afr. J. Trad. Compl. Alt. Med.

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“…Antinociceptive activity of the methanolic extracts of leaves of C. tora was evaluated in the mice by Chidume et al (2002). The extract reduced the nociceptive response of mice to increased force in a dose-dependent manner.…”

Section: Antinociceptive and Spasmogenic Activitymentioning

confidence: 99%

“…The spasmogenic effects of the extract were evaluated on guinea pig ileum, rabbit jejunum and mice intestinal transit. The extract elicited contraction of smooth muscles of guinea pig ileum and rabbit jejunum in a concentrationdependent manner (Chidume et al, 2002). Rajan et al (2009) observed that (in-vivo model of rat) C. tora leaves methanol extract was effective in protecting liver against Carbon tetrachloride (CCl 4 ) induced liver damage.…”

Section: Antinociceptive and Spasmogenic Activitymentioning

confidence: 99%

THE PROBABLE MEDICINAL USAGE OF <i>CASSIA TORA</i>: AN OVERVIEW

Shukla¹

2013

OnLine Journal of Biological Sciences

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Cassia tora (C. tora) is a small shrub budding as weed in Asian and African countries. It is a known edible leafy vegetable taken up by Asians. From time immemorial, different parts of C. tora have found application in Indian and Chinese medicine. Its varying useful medicinal effects are well documented in many publications. In this review we have compiled the traditional medicinal usage of C. tora which have been confirmed by scientific studies.

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“…Seeds have been used as a purgative, probably due to the presence of emodine, aloe-emodine and anthraquinone glycosides 38,39,40 .…”

Section: Anti-inflammatory Effectmentioning

confidence: 99%

Untitled

2011

IJPSR

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Cassia tora Linn. (Family: Leguminosae) is well known plant widely distributed in India and other tropical countries. It is an annual under shrub and grows in wild wasteland. Different parts of the plant (Leaves, seed, and root) are reputed for their medicinal value. It is well recognized traditional medicine as laxative and is useful for treatment of leprosy, ringworm infection, ophthalmic, skin diseases and liver disorders. Several chemical compounds such as Anthraquinone glycosides, Naphthopyrone glycosides, Phenolic compounds, Flavonoids etc. have been isolated from this plant. The present review summarizes the scientific information of various aspects of Cassia tora plant used in traditional system of medicine for variety of purpose. INTRODUCTION:The World Health Organization (WHO) estimates that about 80% of people living in developing countries rely almost exclusively on traditional medicines for their primary health care needs 1 . India is virtually a herbarium of the world. In India, we are using plants and herbs as the basic source of medicine because we are rich in them. Herbals which form a part of our nutrition and provide us an additional therapeutic effect are in demand and Cassia tora is one of such plant.

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Antinociceptive and smooth muscle contracting activities of the methanolic extract of Cassia tora leaf

Cited by 25 publications

References 4 publications

Tribal Formulations for Treatment of Pain: A Study of the Bede Community Traditional Medicinal Practitioners of Porabari Village in Dhaka District, Bangladesh

Tribal Formulations for Treatment of Pain: A Study of the Bede Community Traditional Medicinal Practitioners of Porabari Village in Dhaka District, Bangladesh

THE PROBABLE MEDICINAL USAGE OF <i>CASSIA TORA</i>: AN OVERVIEW

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