Antinociceptive effect of recombinant neuroprogenitor intraspinal transplants in models of peripheral and central neuropathic pain

Jergová, Stanislava; Varghese, M; Collante, D.; Bartley, S.; Gajavelli, Shyam; Sagen, Jacqueline

doi:10.1016/j.jpain.2011.02.159

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Serine-histogranin1

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2012

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“…Intrathecal injection of SHG can block NMDA induced hyperalgesia and allodynia with no apparent adverse motor effects (Siegan & Sagen, 1995) in contrast to findings with another NMDA antagonists, MK-801 (Hama & Sagen, 2002;Hama et al, 2003). Recent results showed potentiation of antinociceptive effect of GABAergic transplant by intrathecally injected SHG in the model of peripheral nerve injury (Jergova et al, 2011b).…”

Section: Serine-histograninmentioning

confidence: 99%

Basic Principles of Peripheral Nerve Disorders

Rayegani¹

2012

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47 years old, is an academic physiatrist who has completed his residency training in PM&R from Shiraz medical university, Iran 1992. He started his academic activities as assistant professor of PM&R in Shohada medical center, Shahid Beheshti university of medical sciences just after passing Iranian board of PM&R examination in which he gained 1st rank. He is one of the founder pioneers for establishing residency training program in the field of PM&R in Tehran, capital of Iran. Professor Rayegani fields of interest include; electrodiagnostic medicine, entrapment syndromes, pain, spinal cord injury and medical education. He supervised more than 20 postgraduate residency theses and published about 19 indexed articles in PubMed and ISI and also more than 30 articles in local medical journals.

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