Antioxidant Activity and Phenolic Compounds Content of Extracts from </>Ceratotheca sesamoides</i> Endl and <i>Striga hermonthica</i> (Delille) Benth Used as Antheminthic in Burkina Faso

Abstract

The revaluation of medicinal plants in the veterinary pharmacopoeia is essential for the development of livestock in Burkina Faso. In order to justify the use of C. sesamoides and S. hermonthica in the treatment of gastrointestinal parasitosis of small ruminants, a quantification of phenolic compounds as well as antioxidant activity and acute toxicité evaluation of both plants were performed. Acute toxicity was evaluated by administering a single dose of 2000 mg/kg body weight of aqueous extract of both plants to mice. The highest total polyphenol content for C. sesamoides was obtained in the ethyl acetate fraction with 47.236 ± 2.57 mgEAG/100mg while that of S. hermonthica was 74.871 ± 2.57 mgEAG/100mg obtained with the n-butanol Fraction. The dichloromethane extract of S. hermonthica obtained the highest total flavonoid content with 7.31 ± 0.48 mgEQ/ 100 while the highest total flavonoid content of C. sesamoides was obtained with ethyl acetate fraction with 5.4273 ± 0.35 mgEQ/100mg. The aqueous extract of C. sesamoides obtained the highest content of condensed tannins with 3.028 ± 0.13 mgEAT/100mg. Both plant's extracts did not show any signs of toxicity in NMRI mice after administration of the dose of 2000 mg/kg.

Application of Biocontrol Agents and Plants Extract Against Fungal Phytopathogens of Vegetable Crops

“…It is reported that no phytochemical studies have been previously done on plant material and extract; however, the plant material is highly beneficial against several diseases and infections [26,27]. This weed is also reported as an antioxidant due to the presence of numerous properties of phenolic compounds including tannins anthocyanins, apigenin and luteolin [28][29][30][31].…”