Antioxidant activity of compounds isolated from the pyroligneous acid, Rhizophora apiculata

Loo, Amanda; Jain, Kavish Kumar; Demirtaş, İbrahim

doi:10.1016/j.foodchem.2007.09.044

Cited by 185 publications

(128 citation statements)

References 51 publications

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“…In our results, it is important to note that Compound 3 (quercetin) showed a higher antioxidant activity compared to standard control (vitamin C). Our results are in line with the study by Loo et al (2008), which reported that three compounds isolated from Rhizophora apiculata had higher scavenging activity than vitamin C. It is well-documented that flavonoids such as quercetin, catechin and kaempferol are potent antioxidants agent 20 times than vitamin C and vitamin E (Chow et al, 2005;Martini et al, 2004). The activity shown by quercetin can be attributed to presence of the 3-and 5-OH groups in A-ring, a catechol moiety of the Bring and the 2,3-double bond in conjugation with a 4-oxofunction of a carbonyl group in the C-ring (Kumarasamy et al, 2002).…”

Section: Dpph Scavenging Assaysupporting

confidence: 94%

“…Of all compounds isolated, compound 3 was the most potent radical scavenger, exhibiting EC 50 value of 1.27 ± 0.25 µg/ml, followed by compound 1 (EC 50 , 2.74 ± 0.10 µg/ml), and Compound 2 (EC 50 , 3.41 ± 0.09 µg/ml) as the least active compound. The lower the EC 50 value the higher is the antioxidant activity (Atoui et al, 2005;Banerjee et al, 2005;Chan et al, 2007;Loo et al, 2008). In our results, it is important to note that Compound 3 (quercetin) showed a higher antioxidant activity compared to standard control (vitamin C).…”

Section: Dpph Scavenging Assaymentioning

confidence: 47%

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Antioxidant activity and cytotoxicity effect of flavonoids isolated from Athrixia phylicoides

Mavundza¹,

Tshikalange²,

Lall³

et al. 2010

J. Med. Plants Res.

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Bioassay-guided fractionation of an ethanolic extract from aerial parts of Athrixia phylicoides using silica and sephadex column chromatography led to the isolation of three flavonoids. The compounds were identified as: 5-hydroxy-6,7,8,3',4',5'-hexamethoxyflavon-3-ol (1), 3-0-demethyldigicitrin (2), and Quecertin (3). Isolated compounds together with ethanol crude extract were tested for antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH)-spectrophotometric assay, while cytotoxicity effect was determined using XTT colorimetric assay. The crude extract showed a concentration-dependent radical scavenging activity with EC 50 value of 10.64 ± 0.08 µg/ml. Compound 3 was the most potent radical scavenger, exhibiting EC 50 value of 1.27 ± 0.25 µg/ml, followed by compound 1 and 2 showing 2.74 ± 0.10 and 3.41 ± 0.09 µg/ml respectively. The crude extract showed no or little toxicity on Vero cells at lower concentrations tested exhibiting the IC 50 value of 107.8 ± 0.13 µg/ml. Compound 3 showed minimal toxicity effect by exhibiting IC 50 value of 81.38 ± 0.33 µg/ml as compared to compound 2 (IC 50 , 28.92 ± 0.12 µg/ml) and compound 1 (IC 50 , 27.91 ± 0.18 µg/ml). The results obtained from this study provide a clear rationale for the medicinal uses of A. phylicoides.

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Section: Dpph Scavenging Assaysupporting

confidence: 94%

Section: Dpph Scavenging Assaymentioning

confidence: 47%

Antioxidant activity and cytotoxicity effect of flavonoids isolated from Athrixia phylicoides

Mavundza¹,

Tshikalange²,

Lall³

et al. 2010

J. Med. Plants Res.

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“…According to the results, we note that there was a significant difference between the results of phosphomolybdenum and ABTS/DPPH assays, which can be explained by the fact that the hydrogen transfer electrons from antioxidant varies with its chemical structure [32]. In addition, non-phenolic compounds such as tocopherols and ascorbic acid may also act as reducer, thus cannot be observed a positive relationship between phenolic content and phosphomolybdenum reduction activity [33].…”

Section: Resultsmentioning

confidence: 82%

Antioxidant Activity and Phytochemical Profile of <i>Spondias tuberosa</i> Arruda Leaves Extracts

Uchôa¹,

Oliveira²,

Pereira³

et al. 2015

AJPS

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Spondias tuberosa Arruda (umbuzeiro), a Brazilian semiarid plant, is a species of great economic, social, and ecological importance. In folk medicine, the leaves have been used in the treatment of diabetes, inflammation, stomach and uterine pains, and constipation. In this study, the antioxidant properties of ethyl acetate and methanol leaves extracts were evaluated in vitro using different methods: free radicals elimination by DPPH and ABTS assays, and transition metal reduction by phosphomolybdenium assay. In addition, a phytochemical study was also carried out. The methanolic leaves extracts showed the strongest antioxidant activity and the higher values for total phenolic and flavonoids. The results showed that S. tuberosa leaves have antioxidant activity and this seems to be related to the phenolic content.

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“…Pyroligneous acid (PA) is a brownish-yellow acidic liquid derived from the slow pyrolysis of biomass in an oxygen-free environment (Loo et al 2008). PA is obtained by the condensation of pyrolysis vapor, which is a by-product of making charcoal (Mathew and Zakaria 2015).…”

Section: Introductionmentioning

confidence: 99%

Fractionation of Pyroligneous Acid: The First Step for the Recovery of Levoglucosan

Fang¹,

Li²,

Yi³

et al. 2016

BioResources

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Levoglucosan (LG) obtained from lignocellulosic biomass exhibits great potential as a specific tracer for biomass burning aerosols and as a raw material for synthesizing stereoregular polysaccharides. One potentially viable source of LG is pyroligneous acid (PA). This study investigated the effects of heating temperature on the extraction capability and the chemical composition of distillate and residual fractions. The results demonstrated that vacuum distillation extracted the acids, alcohols, ketones, aldehydes, and other organic matter. When the heating temperature was above 80 °C, the moisture content of the residual fraction was unchanged. The chemical composition of residual fraction was analyzed by gas chromatography-mass spectrometry (GC-MS). The analysis showed that the relative content of the LG, as obtained from the 90 °C distillation temperature, was 75.6%. Thus, it can be used as raw material for subsequent purification.

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Antioxidant activity of compounds isolated from the pyroligneous acid, Rhizophora apiculata

Cited by 185 publications

References 51 publications

Antioxidant activity and cytotoxicity effect of flavonoids isolated from Athrixia phylicoides

Antioxidant activity and cytotoxicity effect of flavonoids isolated from Athrixia phylicoides

Antioxidant Activity and Phytochemical Profile of <i>Spondias tuberosa</i> Arruda Leaves Extracts

Fractionation of Pyroligneous Acid: The First Step for the Recovery of Levoglucosan

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Antioxidant activity of compounds isolated from the pyroligneous acid, Rhizophora apiculata

Cited by 185 publications

References 51 publications

Antioxidant activity and cytotoxicity effect of flavonoids isolated from Athrixia phylicoides

Antioxidant activity and cytotoxicity effect of flavonoids isolated from Athrixia phylicoides

Antioxidant Activity and Phytochemical Profile of &lt;i&gt;Spondias tuberosa&lt;/i&gt; Arruda Leaves Extracts

Fractionation of Pyroligneous Acid: The First Step for the Recovery of Levoglucosan

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Antioxidant Activity and Phytochemical Profile of <i>Spondias tuberosa</i> Arruda Leaves Extracts