Over the centuries, humanity has known and utilized some sacred oils extracted from their medicinal plants for therapeutic purpose. They are considered as good source of bioactive compounds having a wide range of vital biological activities. Aromatic oils have been a part of human history for more than 3,500 years BC and appeared with regularity throughout all major civilizations down the ages, with uses ranging from religious ritual, food flavoring, medicines, perfumery and the masking of bad odors. It is impossible to date exactly when plants were first used medicinally, since such a development would have taken place over thousands of years. During recent decades, many researchers have investigated the mechanisms of action and the therapeutic use of essential oils as physical, emotional, and spiritual well-being. This review, highlights on some sacred essential oils extracted from important traditional medicinal plants that possesses several pharmacological properties, considering that the safety and versatility of this these supplement should allow for its use in numerous pathological conditions.