Antioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp. millefolium Afan. (Asteraceae)

Candan, Ferda; Ünlü, Mehmet; Tepe, Bektaş; Daferera, Dimitra; Polissiou, Moschos G.; Sökmen, Atalay; Akpulat, H. Aşkın

doi:10.1016/s0378-8741(03)00149-1

Cited by 500 publications

(318 citation statements)

References 26 publications

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“…A atividade antimicrobiana foi realizada (Mislivec et al, 1992;Swanson et al, 1992) e a determinação da concentração inibitória mínima (CIM) (Candan et al, 2003).…”

Section: Atividade Antimicrobianaunclassified

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Atividades antimicrobiana e leishmanicida das sementes de Pterodon emarginatus Vogel

Dutra¹,

Braga²,

Coimbra³

et al. 2009

Rev. bras. farmacogn.

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"Antimicrobial and leishmanicidal activities of seeds of Pterodon emarginatus". The present work investigated the antimicrobial and leishmanicidal activities of seeds of Pterodon emarginatus. The tests of diffusion in agar (10, 25 and 50 mg) and determination of minimum inhibitory concentration (MIC) were performed using essential oil (EO) obtained from seeds using the standard microorganisms: Staphylococcus aureus ATCC 25923, Streptococcus mutans ATCC 25175, Pseudomonas aeruginosa ATCC 90271, Escherichia coli ATCC 10530 and Candida albicans ATCC 10231. Leishmanicidal activity of the EO and fractions (6.25 -100 μg/ml) obtained of seeds of P. emarginatus was evaluated in vitro using L. amazonensis and L. chagasi promastigote forms. The EO inhibited the growth of S. aureus (MIC = 2.5 mg/ml). The hexane (IC 50 = 50.06 µg/ ml) and butanol (IC 50 = 46.65 µg/ml) fractions showed activity against L. amazonensis promastigote forms, but did not against L. chagasi promastigote forms. The results indicate that the bioactive molecules present in the seeds of P. emarginatus can be used as prototype for the development of drug and/or as source pharmaceutical material.

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“…A atividade antimicrobiana foi realizada (Mislivec et al, 1992;Swanson et al, 1992) e a determinação da concentração inibitória mínima (CIM) (Candan et al, 2003).…”

Section: Atividade Antimicrobianaunclassified

“…Os tubos foram incubados em ambiente aeróbico a temperatura de 37 °C por 24 horas. A CIM foi determinada através da observação de turvação dos meios de cultura, após o período de incubação (Candan et al, 2003).…”

Section: Determinação Da Concentração Inibitória Mínima (Cim)unclassified

Atividades antimicrobiana e leishmanicida das sementes de Pterodon emarginatus Vogel

Dutra¹,

Braga²,

Coimbra³

et al. 2009

Rev. bras. farmacogn.

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“…Antinociceptive and anti-inflammatory [31], human erythrocyte and leukocyte protective [32], antispasmodic [33], antimicrobial [34] and antioxidant activities [30,35,36] of different Achillea species growing in Turkey were previously reported. A. latiloba extracts in acetone, ethyl acetate, ethanol, methanol and dimethyl sulfoxide (DMSO) affected bacteria and fungal growth because they probably contain tannins, essential oils, flavonoids and organic acids or other similar substances.…”

Section: Resultsmentioning

confidence: 91%

Screening of various solvents and extracts of Achillea latiloba Ledeb. ex Nordm for antibacterial and antifungal activities

Ertürk

2014

Herba Polonica

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S u m m a r yIn this study the antibacterial and antifungal activities of extracted Achillea latiloba Ledeb. ex Nordm (Asteraceae) samples in acetone, ethyl acetate, ethanol, methanol and dimethyl sulfoxide (DMSO) from Trabzon Province (Turkey) were investigated. Antimicrobial activity of A. latiloba varied depending on the extract of samples, dosage of extracts, and the extraction solvents for all test microorganisms. Staphylococcus aureus, Streptococcus salivarius, Klebsiella pneumoniae, Escherichia coli, Salmonella enteritidis, Streptococcus pneumoniae, Bacillus cereus, Listeria monocytogenes, Streptococcus mutans, Pseudomonas aeruginosa, Bacillus licheniformis, Micrococcus luteus, Bacillus subtillis, Proteus vulgaris andCandida albicans were studied with use of disc diffusion and agar dilution method. The results indicated that each of the crude extracts of Achillea latiloba exhibited a more or less pronounced antibacterial and antifungal potency both in Gram-positive and Gram-negative bacteria and fungi. While in the Gram-negative group, the most sensitive microorganism to Achillea latiloba were S. enteritidis and Streptococcus mutans which is Gram-positive. In the Gram-positive group, the microorganisms most sensitive to Achillea latiloba were Streptococcus mutans and L. monocytogenes. However, the least sensitive microorganism was P. vulgaris. The results presented in this paper suggest that Achillea latiloba possesses additional antimicrobial activities that has an effect against some Gram-negative, Grampositive bacteria and fungi.

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“…An infusion or a decoction of the flowers and leaves is useful in colds, to quiet the nerves, to treat colic, to suppress hemorrhages, and as an emmengogue [3,4]. The essential oils of A. millefolium have shown in vitro antioxidant and antimicrobial properties [5]. The plant also has a long history as a powerful 'healing herb' used topically for wounds, cuts and abrasions.…”

Section: Introductionmentioning

confidence: 99%

Isolation and Structure Determination of Three New Sesquiterpenoids from Achillea millefolium

Farooq

Khan

et al. 2012

Zeitschrift Für Naturforschung B

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Phytochemical investigation of the whole plant of Achillea millefolium led to the isolation of three new sesquiterpenes which were trivially named as sesquiterpene lactone-esters A and B (1 and 2), and sesquiterpene lactone-diol (3). The structures of these compounds were determined with the help of one-and two-dimensional (1D and 2D) NMR techniques including 1 H NMR, 13 C NMR, HMQC, HMBC, COSY, and NOESY experiments.

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Antioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp. millefolium Afan. (Asteraceae)

Cited by 500 publications

References 26 publications

Atividades antimicrobiana e leishmanicida das sementes de Pterodon emarginatus Vogel

Atividades antimicrobiana e leishmanicida das sementes de Pterodon emarginatus Vogel

Screening of various solvents and extracts of Achillea latiloba Ledeb. ex Nordm for antibacterial and antifungal activities

Isolation and Structure Determination of Three New Sesquiterpenoids from Achillea millefolium

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