Antioxidant and antimicrobial phenolic compounds from extracts of cultivated and wild-grown Tunisian Ruta chalepensis

Abstract

The antioxidant and antibacterial activities of phenolic compounds from cultivated and wild Tunisian Ruta chalepensis L. leaves, stems, and flowers were assessed. The leaves and the flowers exhibited high but similar total polyphenol, flavonoid, and tannin content. Moreover, two organs showed strong, although not significantly different, total antioxidant activity, 2,2-diphenyl-1-picrylhydrazyl scavenging ability, and reducing power. Investigation of the phenolic composition showed that vanillic acid and coumarin were the major compounds in the two organs, with higher percentages in the cultivated organs than in the spontaneous organs. Furthermore, R. chalepensis extracts showed marked antibacterial properties against human pathogen strains, and the activity was organ- and origin-dependent. Spontaneous stems had the strongest activity against Pseudomonas aeruginosa. From these results, it was concluded that domestication of Ruta did not significantly affect its chemical composition and consequently the possibility of using R. chalpensis organs as a potential source of natural antioxidants and as an antimicrobial agent in the food industry.

Antioxidant and hepatoprotective effects ofAsparagus albusleaves in carbon tetrachloride-induced liver injury rats

“…Other different results were obtained by Fan, Yuan, Wang, Gao, and Huang () in the case of A. officinalis who identified five antioxidant compounds, namely ferulic acid, kaempferol, quercetin, rutin, and isorhamnetin. Our results corroborated those of Ouerghemmi et al () who found high proportion of vanillic acid compound in Ruta chalepensis leaf extract. This later showed a strong antioxidant and antimicrobial activities.…”

Release of phenolic acids from sunflower and rapeseed meals using different carboxylic esters hydrolases from Aspergillus niger

“…Free caffeic (CA) acid is also found in SFM but accounts for just 0.5 % of the TPC content (Guo et al, 2017;Szydłowska-Czerniak et al, 2011;Weisz et al, 2009). Phenolic acids, particularly hydroxycinnamic acids, are bioactive molecules with interesting properties that include antioxidant (Gullón et al, 2018;Shahidi and Ambigaipalan, 2015), anti-inflammatory (Oueslati et al, 2012) and antimicrobial (Ouerghemmi et al, 2017) activities among others. These bioactive properties can be enhanced by modifying the hydrophilic/hydrophobic balance of the molecules (Laguerre et al, 2013;Lecomte et al, 2010;Szydłowska-Czerniak et al, 2018).…”

Effect of Introducing the Jordanian Common Rue (Ruta chalepensis L.) on Liver Enzymes and Lipid Peroxidation in Adult Male Sprague Dawley Rats Toxified With Paracetamol

“…Antioxidants are compounds that can delay or inhibit the oxidation of lipids or other molecules by inhibiting the initiation or propagation of oxidizing chain reactions (Volf et al, 2013). Nowadays, antioxidant agents of natural origin have attracted special interest because they can protect the human body from free radicals, due to its high content of polyphenolic compounds (Pandey & Rizvi, 2009). Accordingly, antioxidants can protect the body from reactive oxygen species (ROS) that damages cells and prevent carcinogenesis by scavenging them.…”

“…Plants such as Ruta chalepensis L. are considered a valuable source of bioactive components such as natural antioxidants which possess defense mechanism against ROS (Ouerghemmi et al, 2017;Romojaro, Botella, Obón, & Pretel, 2013). Polyphenols constitute the main bioactive phytochemicals that have been proven effective in the prevention of certain chronic diseases such as coronary heart diseases, cancers and diabetes due to their free radical-scavenging activities (Lamien-Meda et al, 2008).…”