Antioxidant and immunobiological activity of water-soluble polysaccharide fractions purified from Acanthopanax senticosu

Chen, Ruizhan; Liu, Zhiqiang; Zhao, Ji-Xing; Chen, Ruiping; Meng, Fansen; Zhang, Min; Ge, Wencheng

doi:10.1016/j.foodchem.2010.12.143

Cited by 215 publications

(100 citation statements)

References 25 publications

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“…At a concentration of 10 mg/mL, polysaccharides extracted from Ganoderma lucidum showed good superoxide anion scavenging activity (56%) (Xu et al, 2009). Compared to these results, RNLP I had a stronger scavenging activity on superoxide radicals, which may have been due to the presence of a sufficient number of strong electrophilic groups such as ketones or aldehydes (Chen et al, 2011).…”

Section: Scavenging Effects On Superoxide Radicalscontrasting

confidence: 56%

Optimisation of pressurised water extraction of polysaccharides from blackcurrant and its antioxidant activity

Cai

et al. 2016

Food Chemistry

126

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Section: Scavenging Effects On Superoxide Radicalscontrasting

confidence: 56%

Optimisation of pressurised water extraction of polysaccharides from blackcurrant and its antioxidant activity

Cai

et al. 2016

Food Chemistry

126

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“…DPPH radical scavenging activity DPPH (1,1-diphenyl-2-picrylhydrazyl) is a compound that has been widely used to determine the free-radical scavenging ability of different materials (CHEN et al, 2011). Alcoholic solutions of DPPH have a characteristic maximum absorption at 517 nm.…”

Section: Resultsmentioning

confidence: 99%

Antioxidant activity of polysaccharides extracted from Lentinus edodes mycelia and their protective effects on INS-1 cells

Liu¹,

Wang²,

Yu³

et al. 2016

Biosci. J.

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ABSTRACT:The disruption of the delicate balance between the generation of reactive oxygen species (ROS) and antioxidant scavenging systems can lead to many health problems. Polysaccharides extracted from fungi fruit body and myceliums have several potential health benefits. In this study, the antioxidant capacity and cell protective effects of a polysaccharide isolated from Lentinus edodes mycelia (LMP) were investigated. The antioxidant properties of LMP were screened using radical scavenging (1, 1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl, and superoxide anion), reducing power and inhibition of lipid peroxidation assays. Intracellular reactive oxygen species (ROS), in response to H 2 O 2 , was determined by the dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay. Rat insulinoma (INS-1) cells apoptosis was detected using flow cytometry analysis. The results showed that LMP exhibited significantly strong radical scavenging activity. At the concentration of 2.0 mg mL -1 , DPPH radical, hydroxyl radical, and superoxide anion radical scavenging rates are 80.32 ± 2.58%, 92.56 ± 3.11% and 93.73 ± 2.82%, respectively. The reducing power and inhibition of lipid peroxidation activity of LMP were as strong as the positive control. LMP alleviated the intracellular reactive oxygen species level and inhibited islet cell apoptosis significantly. The results open perspectives for studies of LMP in the treatment of diabetes.

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“…For the validation of this method, ascorbic acid was run as a standard along with the samples. The DPPH free radical is a stable free radical, which has been widely used as a tool for testing the freeradical scavenging activities of antioxidants 15 . The essential oil of G. pulchella provided dose-dependent DPPH scavenging efficacy, and the scavenging value reached 72.34 at the concentration of 200 μg/ml.…”

Section: Resultsmentioning

confidence: 99%

Analysis of the Essential Oil from Gaillardia pulchella Foug. and its Antioxidant Activity

et al. 2013

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Antioxidant and immunobiological activity of water-soluble polysaccharide fractions purified from Acanthopanax senticosu

Cited by 215 publications

References 25 publications

Optimisation of pressurised water extraction of polysaccharides from blackcurrant and its antioxidant activity

Optimisation of pressurised water extraction of polysaccharides from blackcurrant and its antioxidant activity

Antioxidant activity of polysaccharides extracted from Lentinus edodes mycelia and their protective effects on INS-1 cells

Analysis of the Essential Oil from Gaillardia pulchella Foug. and its Antioxidant Activity

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