Antioxidant Capacity Connection with Phenolic and Flavonoid Content in Chinese Medicinal Herbs

Li, Mengfei; Paré, Paul W.; Zhang, Jinlin; Kang, Tianlan; Zhang, Zhen; Yang, Deok‐Chun; Wang, Kepeng; Xing, Hua

doi:10.25135/rnp.24.17.08.138

Cited by 52 publications

(56 citation statements)

References 34 publications

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“…It was known that differences in antioxidant activity in plant materials depend on the cultivar, growing environment, extraction method, and so on [ 36 ]. Li et al studied 93 traditional Chinese herbal medicines and found that the highest DPPH scavenging activities of P. lactiflora were 94.48% [ 37 ]. Zhang et al enriched the total flavonoids of Paeonia ostii flowers via polyamide resin columns and found that the extracts with higher total flavonoid content had higher antioxidant activity [ 38 ].…”

Section: Resultsmentioning

confidence: 99%

UPLC-ESI-MS/MS Analysis and Evaluation of Antioxidant Activity of Total Flavonoid Extract from Paeonia lactiflora Seed Peel and Optimization by Response Surface Methodology (RSM)

Guo-qing

Shen

Wei

et al. 2021

BioMed Research International

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In this study, the ultrasound-assisted extraction (UAE) of flavonoid from Paeonia lactiflora seed peel was optimized by response surface methodology (RSM). Single-factor experiments and a three-factor three-level Box-Behnken design (BBD) were performed to explore the effects of the following parameters on flavonoid extraction: ethanol concentration ( X 1 ), liquid-solid ratio ( X 2 ), and ultrasonic time ( X 3 ). The results showed that the optimal flavonoid yield (10.9045 mg RE/g) was as follows: ethanol concentration 62.93%, ultrasonic time 64.56 min, and liquid-solid ratio 24.86 mL/g. The optimized extract of P. lactiflora seed shell was further analyzed by UPLC-ESI-MS/MS, and 20 main flavonoids were identified and quantified, among which protocatechuic acid, vanillic acid, 4-hydroxybenzoic acid, and 3,4-dihydroxybenzaldehyde had the highest content. Furthermore, the results of the antioxidant test showed that the P. lactiflora seed peel extract obtained under optimized UAE conditions exhibited good antioxidant activity. The experimental results showed that ultrasound-assisted extraction was a fast, efficient, and simple method for extracting active ingredients from P. lactiflora seed peel, thereby making this byproduct a promising source of compounds in food and healthcare sectors.

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Section: Resultsmentioning

confidence: 99%

UPLC-ESI-MS/MS Analysis and Evaluation of Antioxidant Activity of Total Flavonoid Extract from Paeonia lactiflora Seed Peel and Optimization by Response Surface Methodology (RSM)

Guo-qing

Shen

Wei

et al. 2021

BioMed Research International

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“…mineral deficiency, secondary metabolites utilize available plant primary resources or carbon skeleton resulting in a more reduction of plant growth. Li et al (2018) concluded that there was a positive correlation between antioxidant activity and phenolics in Chinese medicinal herbs. In agreement with this view, the significant increase in antioxidant activity of starved Azolla was accompanied with increase of phenolics content and decrease of growth.…”

Section: Discussionmentioning

confidence: 99%

“…Reactive oxygen species (ROS) such as superoxide (O 2 •− ), hydroxyl (OH .-), peroxyl (ROO . ) radicals as well as non-free radical species such as hydrogen peroxide (H 2 O 2 ) and singlet oxygen ( 1 O 2 ) are generated in chloroplast, mitochondria and peroxisome as a natural by-product of the normal metabolism and have vital roles in cell signaling and homeostasis (Gill & Tuteja, 2010;Li et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Nutrient Starvation Enhances the Phenolic Compounds and Antioxidant Activity in Azolla caroliniana Plant

2019

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T HE AIM of this study is evaluating the effects of nutrients deprivation in growth media of Azolla caroliniana plant on growth and production of various phenolic components and antioxidant activity. Nutrient-deficient cultures (0.2, 0.1, 0.05 strength Hoagland solution) of Azolla plants resulted in a significant reduction in Azolla biomass, particularly with 0.05 strength compared to those grown on nutrient-sufficient culture (control). The doubling time (DT) and relative growth rate (RGR) were significantly affected with different Hoagland strength and that was accompanied with a significant accumulation of H 2 O 2 and MDA. Anthocyanins, total flavonoids and total phenolics were enhanced in starved-Azolla. HPLC analysis of phenolic acids revealed a significant increase in caffeic, o-coumaric and t-cinnamic acids in Azolla grown on 0.2 strength Hoagland culture, whereas coumaric acid was markedly accumulated in Azolla plants grown on 0.1 strength media. There was a significant increase in phenylalanine ammonia lyase (PAL) and antioxidant activities in starved Azolla. The results indicated that, the antioxidant activity might depend mainly on phenolic compounds.

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“…Phenolic and flavonoid compounds widely exist in plants and have been a major contributor to the antioxidant activity. 25…”

Section: Dpph Radical Scavenging Capacitymentioning

confidence: 99%

The In Vitro Antioxidant Activity and Phytochemicals of Locally Consumed Plant Foods from Quezon Province, Philippines

Yu¹,

Cabrera²,

Bueno³

et al. 2020

Acta Med Philipp

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Background. Quezon province has been one of the primary agricultural sources of vegetables and crops in southern Luzon due to its diverse agricultural topography. Having increased dietary awareness, consumption of antioxidant-rich foods has become relevant. Objectives. Thirteen (13) methanolic extracts of endemic Quezon plant foods were evaluated for phytochemical constituents and antioxidant potential.Methods. The plant extracts were subjected to in vitro antioxidant assays, which include DPPH [2,2-diphenyl-1picrylhydrazyl], FRAP [Fluorescence recovery after photobleaching], metal chelation, superoxide, nitric oxide, hydroxyl radical scavenging activities and MTT [ (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide)] reduction. Qualitative phytochemical analysis were also employed. Results. P. umbellatum, locally known as kamamba and C. longa, locally known as luyang dilaw showed high antioxidant activity using DPPH and MTT assays by 82.46±0.75% and 82.35±1.79% and 78.46±0.71% and 60.97±2.60% at 66.67 μg/mL, respectively. FRAP assay revealed a comparable reducing power with BHT (butylated hydroxytoluene) (93.61±0.56%) at 72.15 μg/mL in C. longa (92.49±1.32%), P. umbellatum (92.38±0.64%), and Z. officinale (90.33±2.06%) (luya), but found with low metal chelating activity. The highest activity against hydroxyl radical were observed in S. edule (sayote) (34.30±1.88%), P. edulis (pasyonaryo) (33.48±1.34%) and D. philippinensis (katmon) (34.71±0.85%) at 45.5 μg/mL. On the other hand, Z. officinale, C. esculenta (gabi), V. unguiculata (sitaw) fruit and D. philippinensis showed dual action, as antioxidant and as pro-oxidant, in Superoxide Scavenging and Nitric Oxide assays. Quezon province plant foods contain flavonoids, phenolic compounds, glycosides and coumarins and quinones which may explain their behavior as antioxidant.Conclusion. The study revealed that different plant foods showed different capacity to scavenge particular oxidants. However, P. umbellatum and C. longa may be considered promising sources of natural antioxidants.

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Antioxidant Capacity Connection with Phenolic and Flavonoid Content in Chinese Medicinal Herbs

Cited by 52 publications

References 34 publications

UPLC-ESI-MS/MS Analysis and Evaluation of Antioxidant Activity of Total Flavonoid Extract from Paeonia lactiflora Seed Peel and Optimization by Response Surface Methodology (RSM)

UPLC-ESI-MS/MS Analysis and Evaluation of Antioxidant Activity of Total Flavonoid Extract from Paeonia lactiflora Seed Peel and Optimization by Response Surface Methodology (RSM)

Nutrient Starvation Enhances the Phenolic Compounds and Antioxidant Activity in Azolla caroliniana Plant

The In Vitro Antioxidant Activity and Phytochemicals of Locally Consumed Plant Foods from Quezon Province, Philippines

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