Antioxidative Activities and Whitening Effects of Ethyl Acetate Fractions from The Immature Seeds of Abeliophyllum distichum

장태원,; Ho, Park Jae

doi:10.5352/jls.2017.27.5.536

Cited by 7 publications

(2 citation statements)

References 31 publications

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“…In addition, a clinical trial confirmed the viability of using AARE as a natural skin-whitening cosmetic product [14]. The skin-whitening effect of hot-water-extracted A. asphodeloides was mainly due to its inhibitory effect on melanin biosynthesis and tyrosinase activity, which was confirmed by evaluating the expressions of tyrosinase, TRP-2, and MITF using a reverse transcription-polymerase chain reaction (RT-PCR) [15][16][17].…”

Section: Introductionmentioning

confidence: 74%

The Assessment of the Skin-Whitening and Anti-Wrinkling Effects of Anemarrhena asphodeloides Bunge Root Extracts and the Identification of Nyasol in a Developed Cream Product

Lee

Jang²,

Choi

2023

Cosmetics

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Anemarrhena asphodeloides Bunge (A. asphodeloides Bunge) root extract contains nyasol as its main ingredient. Nyasol was extracted and prepared as a cosmetic raw material in 95% ethanol. To identify nyasol as a marker compound qualitative analysis was performed using ultra-performance liquid chromatographyi coupled with electrospray ionization–tandem mass spectrometry. Below a nyasol content of 12 μg/mL, the root extract exhibited negligible cytotoxicity. In this concentration range, melanin production in B16F10 mouse melanoma cells decreased as the concentration of nyasol increased, indicating a skin-whitening effect. In addition, an antiwrinkling effect was confirmed by evaluating the inhibition of MMP-1 protein expression in TNF-α-treated HaCaT cells by either A. asphodeloides Bunge root extract (>0.31 μg/mL) or nyasol (>0.25 μg/mL). High-performance liquid chromatography-coupled with a photodiode detector array was used to show that our extract contained 5.06 ± 0.01% nyasol. Furthermore, when this analysis method was applied for the quality control of a cream product containing 2 wt.% of A. asphodeloides Bunge root extract, the measured content of nyasol (0.1%) was over 90% of the nominal quantity. Therefore, the product was deemed to be within the required quality standards.

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Section: Introductionmentioning

confidence: 74%

The Assessment of the Skin-Whitening and Anti-Wrinkling Effects of Anemarrhena asphodeloides Bunge Root Extracts and the Identification of Nyasol in a Developed Cream Product

Lee

Jang²,

Choi

2023

Cosmetics

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“…The pharmacological effects of medicinal plants, which have been used empirically in the private sector, are often generally described as antioxidant effects. It has been reported that the antioxidant effects of medicinal plants are better than fruits and vegetables consumed in daily life [3,4]. Stachys sieboldii Miq.…”

Section: Introductionmentioning

confidence: 99%

Study on the Application of Natural Substances to Cosmeics

Kwon¹

2020

Ijbsa

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Background/Objectives: This study was conducted on the application of natural cosmetics using Stachys sieboldii Miq. Roots and their Antioxidant, anti-aging and whitening. Methods/Statistical analysis: The DPPH radical scavenging activity of Stachys sieboldii Miq. root extract was increased in a concentration-dependent manner in an antioxidant activity test. Its ABTs radical scavenging activity was 94.32±0.12% at a concentration of 1000 μg/mL, and its collagenase inhibitory activity was 39.4±2.52% at the same level of concentration in an anti-aging activity test. Findings: These findings suggest that Stachys sieboldii Miq. roots have potential antioxidant, whitening and anti-aging effects. Improvements/Applications: It is deemed that Stachys sieboldii Miq. root extract can be effectively used in the development of new functional cosmetic ingredients.

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Comparison of biological activity between Stellaria aquatica seed extracts

Cho¹,

Kang²,

Kim³

et al. 2019

Korean Journal of Food Preservation

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Stellaria aquatica, belong to the family Caryophyllaceae (commonly known as the carnation family), is a perennial plant found in subtropical and temperate regions. In addition, the seeds of S. aquatica are known to be polyphenol-rich; however, the biological activities of S. aquatica seeds have not yet been evaluated. To enhance the use of S. aquatica seeds as functional food and natural medicine, the total polyphenolic content, and anti-oxidant, anti-cancer, and immune-modulatory activities of S. aquatica seed extracts were investigated. The radical scavenging and reducing power activities of 1,000 μg/mL S. aquatica seed extracts were similar to those of BHT and α-tocopherol. In addition, total polyphenol and flavonoid contents of S. aquatica seed extracts were the highest in 70% EtOH extract (27.30 mg GAE/g and 23.22 mg QE/g, individually). In the case of HepG2, A549, MCF-7, and B16 cells, IC 50 value of the 70% EtOH extract was lesser than that of other extracts, whereas the lowest IC 50 activity of EtOH extracts was noted in HT-29 and PC-3 cells. Furthermore, EtOH, MeOH and 70% EtOH extract-induced cancer cell death was related to apoptosis. In RAW 264.7 macrophages, 70% EtOH extract significantly improved immune-modulatory activity by increasing nitric oxide (NO) production without inducing significant cytotoxicity. Taken together, our results provide important insights into the bioactive potential of S. aquatica seed extracts as functional food ingredient and natural medicine. Key words：anti-cancer, anti-oxidant, immune-modulatory activity, Stellaria aquatica seed extractComparison of biological activity between Stellaria aquatica seed extracts 229

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Antioxidative Activities and Whitening Effects of Ethyl Acetate Fractions from The Immature Seeds of Abeliophyllum distichum

Cited by 7 publications

References 31 publications

The Assessment of the Skin-Whitening and Anti-Wrinkling Effects of Anemarrhena asphodeloides Bunge Root Extracts and the Identification of Nyasol in a Developed Cream Product

The Assessment of the Skin-Whitening and Anti-Wrinkling Effects of Anemarrhena asphodeloides Bunge Root Extracts and the Identification of Nyasol in a Developed Cream Product

Study on the Application of Natural Substances to Cosmeics

Comparison of biological activity between Stellaria aquatica seed extracts

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