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On July 27, 2023, Alexey Nikolaevich Kuchmin, the Head of the Department of Propaedeutics of Internal Diseases of the Military Medical Academy, named after S. M. Kirov doctor of Medical Sciences, Professor, and former chief therapist of the Ministry of Defense of the Russian Federation, turned 60 years old. A. N. Kuchmin was born on July 27, 1963, in Mineralnye Vody, Stavropol Territory. After graduation, he entered the Faculty of training doctors for the Navy of the Military Medical Academy named after S. M. Kirov, where he graduated with honors in 1986. For 4 years, he served as the Head of the medical center and the infirmary of the Baltic Fleet Naval Aviation. Since 1990, his life and fate have been inextricably linked with the Department of Propaedeutics of Internal Diseases of the Kirov Military Medical Academy, within the walls of which he has passed through a difficult but bright career path from a 3rd-year cadet to an associate Professor, from a teacher to a Professor and Head of the Department. Here, A. N. Kuchmin joined the scientific, pedagogical, and clinical ideas of Professor N. N. Savitsky. Having started his scientific activity under the guidance of Professor Yu. S. Malov, Alexey Nikolaevich devoted himself to the research of the most pressing issues of cardiology, pulmonology, and physiology. After graduating from the adjunct program in 1993 at the Department of Propaedeutics of Internal Diseases of the Academy, A. N. Kuchmin defended his PhD thesis on “The role of salivary glands in maintaining homeostasis in patients with hypertension”. Since that time, he has been a senior resident, then a teacher, associate Professor, and deputy Head of the Department of Propaedeutics of Internal Diseases (for clinical work) since 2005. In 2003, Alexey Nikolaevich defended his doctoral dissertation on cardiac arrhythmias in patients with bronchial asthma. His research interests now include issues in rapidly developing areas, such as endocrinology, ultrasound diagnostics, and functional diagnostics. During his work as the Chief therapist of the Ministry of Defense of the Russian Federation, A. N. Kuchmin proved himself to be a competent Head of the therapeutic service of the Ministry of Defense of the Russian Federation, particularly during the armed conflict in Abkhazia and Georgia. A. N. Kuchmin’s talent as a clinician and organizer of clinical and expert work was also manifested in his leadership from November 2008 to 2010 in the Department of Therapy of the State Institute of Advanced Training of Doctors of the Ministry of Defense of the Russian Federation and since 2015 in his native Department of Propaedeutics of Internal Diseases of the Military Medical Academy named after S. M. Kirov. In all his positions, Alexey Nikolaevich was and remains a highly professional specialist in his field with several clinical interests and knowledge.
On July 27, 2023, Alexey Nikolaevich Kuchmin, the Head of the Department of Propaedeutics of Internal Diseases of the Military Medical Academy, named after S. M. Kirov doctor of Medical Sciences, Professor, and former chief therapist of the Ministry of Defense of the Russian Federation, turned 60 years old. A. N. Kuchmin was born on July 27, 1963, in Mineralnye Vody, Stavropol Territory. After graduation, he entered the Faculty of training doctors for the Navy of the Military Medical Academy named after S. M. Kirov, where he graduated with honors in 1986. For 4 years, he served as the Head of the medical center and the infirmary of the Baltic Fleet Naval Aviation. Since 1990, his life and fate have been inextricably linked with the Department of Propaedeutics of Internal Diseases of the Kirov Military Medical Academy, within the walls of which he has passed through a difficult but bright career path from a 3rd-year cadet to an associate Professor, from a teacher to a Professor and Head of the Department. Here, A. N. Kuchmin joined the scientific, pedagogical, and clinical ideas of Professor N. N. Savitsky. Having started his scientific activity under the guidance of Professor Yu. S. Malov, Alexey Nikolaevich devoted himself to the research of the most pressing issues of cardiology, pulmonology, and physiology. After graduating from the adjunct program in 1993 at the Department of Propaedeutics of Internal Diseases of the Academy, A. N. Kuchmin defended his PhD thesis on “The role of salivary glands in maintaining homeostasis in patients with hypertension”. Since that time, he has been a senior resident, then a teacher, associate Professor, and deputy Head of the Department of Propaedeutics of Internal Diseases (for clinical work) since 2005. In 2003, Alexey Nikolaevich defended his doctoral dissertation on cardiac arrhythmias in patients with bronchial asthma. His research interests now include issues in rapidly developing areas, such as endocrinology, ultrasound diagnostics, and functional diagnostics. During his work as the Chief therapist of the Ministry of Defense of the Russian Federation, A. N. Kuchmin proved himself to be a competent Head of the therapeutic service of the Ministry of Defense of the Russian Federation, particularly during the armed conflict in Abkhazia and Georgia. A. N. Kuchmin’s talent as a clinician and organizer of clinical and expert work was also manifested in his leadership from November 2008 to 2010 in the Department of Therapy of the State Institute of Advanced Training of Doctors of the Ministry of Defense of the Russian Federation and since 2015 in his native Department of Propaedeutics of Internal Diseases of the Military Medical Academy named after S. M. Kirov. In all his positions, Alexey Nikolaevich was and remains a highly professional specialist in his field with several clinical interests and knowledge.
Atrial fibrillation is one of the most common forms of arrhythmia and is associated with an increased risk of stroke, thromboembolism, and increased mortality among patients with cardiovascular disease. Identifying patients at high risk of developing atrial fibrillation and predicting the likelihood of acute cerebrovascular accidents of cardioembolic origin, as well as other thromboembolic complications, is key to optimizing treatment strategies and preventing complications. This article provides a comprehensive review of existing and new biomarkers used to assess the risk of onset and recurrence of atrial fibrillation, as well as to assess the safety of anticoagulation therapy for this arrhythmia. Genetic, inflammatory and metabolic markers are discussed in detail, as well as the role of oxidative stress in the context of pathophysiological processes, clinical manifestations of the disease and its complications. Particular attention is paid to the evaluation of markers that can be used to predict adverse outcomes and improve diagnostic accuracy. Limitations in the ability to routinely and widely use both existing and promising biomarkers are discussed. Their clinical significance, cost-effectiveness and possibilities for integration into everyday clinical practice are considered. The need for standardization of approaches to the comprehensive assessment of biomarkers, the importance of interdisciplinary collaboration and the development of individualized approaches to the treatment of patients with atrial fibrillation, including the use of biomarker data, are emphasized. Optimizing approaches to assessing patients with atrial fibrillation using current and promising biomarkers can help overcome existing limitations and facilitate their implementation in clinical practice, which in turn will improve diagnosis, treatment and prognosis of patients.
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