Antithyroid Drugs

Thyroid crisis

“…This may have been due to the administration of iodine to a patient rendered euthyroid with potassium perchlorate, the goitrogenic effect of the perchlorate ion being overcome by the iodine (Crooks, 1957).…”

“…Those commonly in use to-day include the thiouracils, carbimazole, and, with somewhat increasing frequency, potassium perchlorate. Their mode of action varying, different techniques of preparation of the patient become necessary in each case (Crooks, 1957;British National Formulary, 1960).…”