“…The authors did not, however, study varied cutoffs relative to luminal attenuation. Similar results were found by Fonseca et al 28 In contrast to the study by these authors, the current study shows in general a stronger predictive value of algorithms using threshold cutoffs relative to luminal attenuation than for fixed threshold protocols. Furthermore, the protocol using luminal attenuation + 100 HU suggests the highest predictive value of protocols studied with an optimal calcium volume cutoff of approximately 1200 mm 3 , despite having a similar or lower average threshold cutoff value than other studied protocols.…”