Aortic Valve Replacement in a Patient with Antiphospholipid Syndrome and Idiopathic Thrombocytopenic Purpura

A 61-year-old woman had a history of deep vein thrombosis of the right leg at the age of 36 years. Primary antiphospholipid syndrome APS had been diagnosed at the age of 38 years, and rapidly progressive glomerulonephritis had developed at 54 year. She started hemodialysis one month before presentation due to deterioration of renal function. This time, she presented to the emergency department with paroxysmal nocturnal dyspnea. Echocardiography showed severe combined aortic stenosis and regurgitation ASR. It was considered that the combination of ASR and construction of an arteriovenous fistula for dialysis had led to congestive heart failure. The patient had also experienced headache and agraphia for several days. Therefore, brain MRI was performed and multiple cerebral infarcts were detected. Early surgery should be considered for ASR, but we planned delayed surgery owing to the complication of acute cerebral infarction. During follow-up observation, a new asymptomatic cerebral infarct was detected. Eventually, aortic valve replacement AVR with a biological valve was performed on day 38 of hospitalization. Because she had highly active primary APS, surgery was performed with oral administration of aspirin, followed by continuous systemic heparinization from the early postoperative period. No perioperative thrombosis or bleeding was noted, and the patient was discharged uneventfully on postoperative day 34. Jpn. J. Cardiovasc. Surg. 48 : 119 124 2019 antiphospholipid syndrome ; multiple cerebral infarcts ; aortic valve replacement ; aortic stenosis and regurgitation

show abstract

Aortic Valve Replacement in a Patient with Primary Antiphospholipid Syndrome and Recurrent Cerebral Infarction

Nagura

Sakata

Sakai

et al. 2019

J. J. C. V. S.

View full text Add to dashboard Cite

show abstract

A Case of Sigmoid Colon Cancer Comorbid Antiphospholipid Antibody Syndrome

Mikamori¹,

Ikenaga²,

Yasui³

et al. 2011

Jpn J Gastroenterol Surg

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Aortic Valve Replacement in a Patient with Antiphospholipid Syndrome and Idiopathic Thrombocytopenic Purpura

Cited by 2 publications

References 5 publications

Aortic Valve Replacement in a Patient with Primary Antiphospholipid Syndrome and Recurrent Cerebral Infarction

Aortic Valve Replacement in a Patient with Primary Antiphospholipid Syndrome and Recurrent Cerebral Infarction

A Case of Sigmoid Colon Cancer Comorbid Antiphospholipid Antibody Syndrome

Contact Info

Product

Resources

About