Apart From the Diet, the Ruminal Microbiota of Lambs Is Modified in Relation to Their Genetic Potential for Feed Efficiency or Feeding Behavior

Marie-Etancelin, Christel; Tortereau, Flavie; Gabinaud, Beatrice; Boggio, Guillermo Martinez; Graverand, Quentin Le; Marcon, Didier; Almeida, Marie-Lea De; Pascal, Géraldine; Weisbecker, Jean Louis; Troegeler‐Meynadier, Annabelle

doi:10.3389/fmicb.2021.759432

Cited by 10 publications

(6 citation statements)

References 46 publications

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“…Similarly, the component and abundance of intestinal microbiota confer the constituents and contents of metabolites in the gut content. 33 The predicted differential metabolic pathways by comparing differentiated metabolites in the KEGG database primarily referred to the vitamin and amino acid metabolism (vitamin B 6 , tryptophan, nicotinate, and nicotinamide metabolism and lysine degradation) and bile acid biosynthesis in the LJPS group compared to those in the con group. Of these, vitamin B 6 , tryptophan, nicotinate, and nicotinamide metabolism and lysine degradation were upregulated, whereas bile acid biosynthesis was downregulated in the LJPS group compared to those in the con group.…”

Section: ■ Resultsmentioning

confidence: 99%

“…This certified that the increased abundance of the microbes in the LJPS-fed group enhanced the level of pyridoxal, nicotinate ribonucleoside, nicotinamide, pyridoxamine, 2-isobutyl-3-methoxypyrazine, and 2-(formylamino)benzoic acid in intestine content, which further improved the productivities, feed efficiency, and health parameters of the ducks. Similarly, the component and abundance of intestinal microbiota confer the constituents and contents of metabolites in the gut content . The predicted differential metabolic pathways by comparing differentiated metabolites in the KEGG database primarily referred to the vitamin and amino acid metabolism (vitamin B 6 , tryptophan, nicotinate, and nicotinamide metabolism and lysine degradation) and bile acid biosynthesis in the LJPS group compared to those in the con group.…”

Section: Discussionmentioning

confidence: 99%

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Laminaria Japonica Polysaccharide Improved the Productivities and Systemic Health of Ducks by Mediating the Gut Microbiota and Metabolome

Liu,

Kim,

Cui

et al. 2023

J. Agric. Food Chem.

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This study investigated the beneficial effects of a Laminaria japonica polysaccharide (LJPS) on the systemic health of ducks by modulating the gut microbiome and metabolome. Our findings demonstrated that the LJPS supplementation enhanced the overall growth performance and physiological immune and antioxidant index of ducks. In addition, the LJPS-fed group significantly increased abundances of intestinal Bacteroides and Prevotellaceae with decreased α-diversity than that in the control group. Among the total of 1840 intestinal metabolites, 186 metabolites were identified to be differentially regulated by LJPS feeding (upregulated 143 metabolites and downregulated 43 metabolites), which is closely associated with some of the growth-related metabolic pathways. Lastly, the correlation analysis recapitulates that the beneficial effects of LJPS underlie the alterations in intestinal microbiota and metabolites. Taken together, LJPS supplementation improved the physiological parameters and richness of some beneficial microbes and upregulated certain metabolic pathways, which facilitated better productivities and systemic health of ducks.

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Section: ■ Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Laminaria Japonica Polysaccharide Improved the Productivities and Systemic Health of Ducks by Mediating the Gut Microbiota and Metabolome

Liu,

Kim,

Cui

et al. 2023

J. Agric. Food Chem.

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“…This indicated that increased microbes in the PTMR group affected the enhanced content of tyrosine, methionine, cysteine, histidine, and indole in the rumen of lambs, which further facilitated the improved performance and G/F of lambs. Similarly, it has been documented that the composition and structure of ruminal microbiota defined the constituents and contents of small molecular metabolites of rumen content ( Morgavi et al, 2015 ; Marie-Etancelin et al, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

Diet Type Impacts Production Performance of Fattening Lambs by Manipulating the Ruminal Microbiota and Metabolome

Zhang

et al. 2022

Front. Microbiol.

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The pelleted total mixed ration (PTMR) has a positive effect on the productivity of fattening lambs. However, whether the beneficial effects are underpinned by altering the rumen microbiota and metabolome that remain unclear. This study aimed to investigate correlations among growth performance, ruminal microbiota, and ruminal metabolome of lambs fed PTMR diet. A total of 100 crossbred (Dorper sheep × Fine-wool sheep) ram lambs at 55 days of age with similar body weight (BW) (13.2 ± 0.5 kg) were randomly allocated to 10 pens that were fed either PTMR (PTMR group) or unpelleted total mixed ration (UPTMR group) with the same dietary ingredients and nutritional contents. The average daily gain (ADG) and average daily feed intake (ADFI) were determined during the 62-day experimental period and ruminal pH, volatile fatty acid (VFA) concentrations, microbiota, and metabolome in the rumen of the lambs were examined at the end of the experiment. Compared to those of the UPTMR group, the PTMR group had greater ADFI (P = 0.002), ADG (P = 0.003), and feed efficiency (G/F) (P < 0.05). Similarly, feeding PTMR increased the concentration of total VFA (TVFA) and the molar proportion of propionate, but decreased the proportion of butyrate and acetate to propionate ratio in the rumen of lambs compared to that in lambs from the UPTMR group (P < 0.05). In addition, the PTMR group demonstrated lowered alpha-diversity of the ruminal microbiota and enhanced the relative abundance of Fibrobacter (P < 0.05), Veillonellaceae (P < 0.05), and the abundance of Rikenellaceae (P = 0.064) in the rumen compared with those in the UPTMR group. Feeding lambs with PTMR significantly upregulated the metabolic pathways involving tryptophan, histidine, cysteine and methionine, β-alanine, tyrosine metabolisms, and steroid biosynthesis. Moreover, the abundance of the microbiota strongly correlated with the altered performance, ruminal VFA, metabolites, and metabolic pathways of lambs. Taken together, feeding PTMR shaped the ruminal microbiota of lambs with decreased diversity, while improving relative abundance of some specific microbes and upregulating certain growth-related metabolic pathways, which contributed to the augmented growth performance and G/F of fattening lambs. Thus, feeding PTMR to fattening lambs for superior production performance and G/F is recommended.

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“…Feed efficiency is a crucial economic indicator in pig production, especially for growing pigs. Generally, the assessment of the factors affecting feed efficiency mainly focuses on the microbiome, genetic selection, and diets [ 19 , 20 ]. However, the digestive ability of animals might be highly correlated to the feed efficiency of farm animals.…”

Section: Discussionmentioning

confidence: 99%

Small Intestinal Digestive Functions and Feed Efficiency Differ in Different Pig Breeds

Cheng

Ding

Azad

et al. 2023

Animals

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Small intestinal growth and health affect its digestion and absorption ability, while little information exists about the small intestinal morphology and function differences among the different pig breeds. Therefore, 90 healthy 35 days of age Taoyuan black (TB), Xiangcun black (XB), and Duroc (DR) pigs (30 pigs per breed) with similar body weight (BW) of the same breed were reared to 185 days of age to evaluate the potential relationship between feed efficiency and small intestinal morphology and function at 80, 125, and 185 days of age. The results show that the TB and XB pigs had lower initial and final BW, ADG, and ADFI and plasma CHO and LDL-C levels, whereas they had higher plasma LIP levels and jejunal trypsin, invertase, lactase, and maltase activities and higher DM, ADF, Tyr, Arg, and His digestibility at 80 days of age compared with the DR pigs. At 125 days of age, TB and XB pigs had lower apparent total tract digestibility and plasma CHO, HDL-C, LDL-C, and NH3 levels; XB pigs had lower DM and NDF digestibility, and TB pigs had higher jejunal lactase and maltase activities. At 185 days of age, TB and XB pigs had lower DM, EE, ADF, and GE digestibility, while having higher plasma ALT and UN levels; TB pigs had higher plasma AST level and jejunal chymase activity. Furthermore, the plasma free amino acid contents, small intestinal VH, and nutrient transporter expression levels differed at different ages. Therefore, the different pig breeds exhibited significantly different growth performance and small intestinal growth, mainly resulting from the differences in digestive enzymes and nutrient transporters in the small intestine.

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Apart From the Diet, the Ruminal Microbiota of Lambs Is Modified in Relation to Their Genetic Potential for Feed Efficiency or Feeding Behavior

Cited by 10 publications

References 46 publications

Laminaria Japonica Polysaccharide Improved the Productivities and Systemic Health of Ducks by Mediating the Gut Microbiota and Metabolome

Laminaria Japonica Polysaccharide Improved the Productivities and Systemic Health of Ducks by Mediating the Gut Microbiota and Metabolome

Diet Type Impacts Production Performance of Fattening Lambs by Manipulating the Ruminal Microbiota and Metabolome

Small Intestinal Digestive Functions and Feed Efficiency Differ in Different Pig Breeds

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