Apnea como forma de presentación de una infección por metapneumovirus humano

Abstract

Apnea as a presenting symptom in human metapneumovirus infectionHuman metapneumovirus (hMPV), a recently described pathogen of lower respiratory tract infections (LRTI), has been detected in 5,4% of Chilean infants hospitalized for LRTI whom are negative for adenovirus, respiratory syncytial virus, influenza and parainfluenza viruses. hMPV may cause bronchiolitis or pneumonia in hospitalized patients, and ocassionally require admission to intensive care units and mechanical ventilation. The infection has been associated with apnea, especially in preterm infants. Nosocomial dissemination has also been described. We present the case of a one-month-of age premature infant with apnea, and infection caused by hMPV of probable nosocomial aquisition. Clinical features of hMPV infection are reviewed and its association with apnea and nosocomial transmission is discussed. hMPV should be included in the routine diagnosis of respiratory viruses in infants with apnea and should be considered among the respiratory pathogens associated with nosocomial transmission.

Apneas e infecciones en lactantes

“…De un total de 11 pacientes, 5 fueron manejados en una unidad de cuidados intensivos y 3 de ellos (27%) presentaron el diagnóstico de EAL a su ingreso (14) . En la literatura nacional existen reportes de casos que atribuyen a Metapneumovirus como causa de EAL (15) . Si bien no existe evidencia consistente, probablemente el Metapneumovirus se comporte muy similar a los que hace el VRS, dada la similitud de otros síntomas relacionados a enfermedades respiratoriaas agudas en población pediátrica (16) .…”

The Impact of a History of Pre-maturity on Viral Respiratory Infections in Children Under 2 Years of Age: A Propensity Score-Matching Analysis of in-hospital Complications and Mortality

“…In general, the etiological diagnosis is made on the basis of clinical data, and an age of <2 years indicates a strong suspicion of VRIs (8). The respiratory infections requiring hospitalization in children under 4 years of age are predominantly of a viral etiology; only 10% are due to rhinoviruses, and the remaining 90% are due to RSV or a combination of RSV and rhinoviruses or bocaviruses (9)(10)(11). Although specific therapies for these viruses are not yet available, viral identification can help reduce antibiotic use (12).…”